Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1195 for “"virulence"”.
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Virulence and Digital Culture
… is a theoretical study of the role of virality/virulence as a predominant technological term in the reproduction of social and cultural information in the digital age. I argue that viral media are not new phenomena, only the name is new. Media have always behaved as viruses; it is only when they …
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On the Evolution of Virulence
… is to study the dynamics behind the evolution of virulence. We examine first the underlying mechanics of linear systems of ordinary differential equations by investigating the classification of fixed points in these systems, then applying these techniques to nonlinear systems. We then seek to …
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Analysis of Vibrio parahaemolyticus Virulence Systems
… of V. parahaemolyticus is attributed to several virulence factors, including two hemolysins and two type III secretion systems (T3SS1 and T3SS2). Herein, we compare the virulence of V. parahaemolyticus POR strains, which harbor a mutation in the T3SS needle apparatus, to the V. parahaemolyticus …
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Streptococcal virulence and the coagulation system.
This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of …
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Regulation of virulence in Salmonella enterica
… this thesis describes regulation of Salmonella virulence genes involved in both invasion and the systemic stages of infection. Salmonella uses the Salmonella Pathogenicity Island I (SPI1) Type Three Secretion System (T3SS) to invade intestinal epithelia in the distal ileum of the host small …
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Maize Streak Virus: diversity and virulence
Zea mays was first introduced to Africa in Ghana by Portuguese traders in the 16th century. The steady spread of maize cultivation since then has made it the most important cereal crop in Africa today. Whereas improved maize genotypes and agricultural techniques enable yearly yields above 10 tons …
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Virulence factors in non-gastric Helicobacters
Thesis (S.M.)--Massachusetts Institute of Technology, Division of Toxicology, 1998.
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Genomics and virulence factors of Fusobacterium necrophorum
… genome and identify and study its putative virulence factors contained using in silico and in vitro analysis. Type strains JCM 3718 and JCM 3724,F. necrophorum subspecies necrophorum (Fnn) and funduliforme (Fnf), respectively, and strain ARU 01 (Fnf), isolated from a patient with LS, were …
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Characterization of Virulence Mechanisms in Vibrio parahaemolyticus
Pages xvi-xix are misnumbered as pages vi-ix.
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Studies on the virulence of Leptospira pomona
Thesis (M.S.)--Michigan State University of Agriculture and Applied Science. Dept. of Microbiology and Public Health, 1957
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Study of virulence factors of Staphylococcus aureus
… host. Both methods have been used to identify virulence genes in S. aureus. The main aim of this project was to find any probable new genes of S. aureus that are essential for biofilm formation and infection mouse model by STM. A library of tagged insertion mutants of S. aureus and a series of …
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Biofilm formation and virulence of Streptococcus pneumoniae
… of specific molecular determinants of distinct virulence phenotypes. Formation of biofilms is an important step in pneumococcal pathogenesis, as they serve as reservoirs of infection and organisms within biofilms are resistant to antimicrobials and host immune defences. The aim of this work was …
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Catalase, Superoxide Dismutase, and Staphylococcus Aureus Virulence
… and superoxide radicals, respectively) and virulence of Staphylococcus aureus.
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Periplasmic determinants of virulence in Salmonella enterica
… S. typhimurium induce the expression of myriad virulence factors in order to successfully establish an infection, this organism must adjust its metabolism to the changing conditions present in the host in order to grow. S. typhimurium has a flexible respiratory chain that is capable of utilizing …
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Potential Approaches to Limiting Group A Streptococcus Virulence
… on two potential approaches to limiting GAS virulence. First, we investigated GAS mechanisms of copper tolerance. Copper plays an important role in the development and maintenance of the human immune system. Macrophages utilize copper as an additional stressor to aid in bacterial killing. In …
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Virulence potential and host response to Cronobacter sakazakii
… multilocus sequence typing. A number of virulence traits have been proposed but have not been studied to date with respect to detailed aspects of the virulence potential and host response. Therefore this project compared 34 isolates of C. sakazakii made up of clonal complex 4 (CC4; 21 …
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Virulence of cryphonectria hypoviruses from previous release sites
… American hypoviruses are evolving decreased virulence, and investigated hypovirus interactions affecting virulence in double-infections. Families of single conidial progeny (SCP), differing in infection status, and derived from six recovered, three release, and three comparison isolates were …
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Mechanisms For Bicarbonate-Mediated Virulence In vibrio Cholerae
… depends on the production of the major virulence factors: cholera toxin (CT) and the toxin co-regulated pilus (TCP). The bacterium responds to signals in the human host that activate a virulence regulatory cascade termed the "ToxR Regulon". The ToxR regulon consists of various …
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Investigation of Novel Virulence Mechanisms In Candida Albicans
… and these genes are involved in well-described virulence mechanisms. The majority of these newly annotated genes were completely unstudied at the outset of this study and I have described the first <em>in vitro </em>and <em>in vivo </em>phenotypic assessments of several of these. Mia1, a …
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