Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 391 for “"virology"”.
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The Biological Age in British Agricultural Virology, 1920s-1960s
… reveals a different facet of the history of virology than seen in comparable accounts: one where the dominance of physicochemical instrumentation and methods did not fully displace biological or natural history-based approaches to virus research. Recent histories of molecular biology and …
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Immunology and virology of HIV-1 infection in Cameroon
This study confirms the widespread existence of highly divergent HIV lineages in Cameroon. While the genetic complexity of the Cameroonian HIV-1 epidemic has potentially serious implications for the design of biomedical interventions, detailed analyses of divergent Cameroonian HIV-1 group M …
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Animations and Diagrams in Virology: Their Effects on Student Learning
… if students learn better, in the context of Virology, from animations or diagrams when presented new information. Participants were chosen from students who attended Kennesaw State University. They were asked to meet in a classroom setting and presented either three animations or diagrams …
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Behavioral Ecology and Associated Virology of Mosquito-Host Interactions in Southern California
<p>Elucidating characteristics of mosquito-host interactions are critical for understanding the ecology and epidemiology of mosquito-borne diseases. In this dissertation, I conducted three studies to explore potential mosquito-host interactions and associated virus infection rates. I first …
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Statistical modelling of performance data for molecular amplification methods in diagnostic virology
Nucleic Acid Technology (NAT), introduced in the late 90s, is a molecular amplification method that can be used for the diagnosis and management of patients with infectious diseases. NAT test results are obtained quicker and are quantified, providing greater information than the positive/negative …
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Viral Factors Influencing Early Infection Events During Ex-Vivo KSHV Infection
… fundamental questions about basic immunology and virology knowledge regarding this virus. Kaposi Sarcoma Herpes Virus (KSHV), also known as Human Herpesvirus 8 (HHV8), is the etiological agent of Kaposi Sarcoma (KS) and other lymphoproliferative cancers, such as Multicentric Castleman’s Disease …
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Bayesian Parameter Estimation on Three Models of Influenza
… models of viral infections have been informing virology research for years. Estimating parameter values for these models can lead to understanding of biological values. This has been successful in HIV modeling for the estimation of values such as the lifetime of infected CD8 T-Cells. However, …
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DISSECTION OF HOST-VIRUS INTERACTIONS IN THE HUMAN CENTRAL NERVOUS SYSTEM
… and Influenza A viruses (IAV). Our comparative virology approach demonstrated a susceptibility and permissiveness to herpesvirus infection, while in contrast neurons did not show any productive infection to either IAV or MPXV. By developing a genome-wide CRISPR/Cas9 screening platform in human …
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The implementation of a rapid sample preparation method for the detection of SARS-CoV-2 in a diagnostic laboratory in South Africa
… preparation method in the Groote Schuur Hospital Virology Diagnostic Laboratory in Cape Town, South Africa.
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The Role of e-Antigen in Hepatitis B Infection
… the knowledge of scientists for many years. In virology, particularly in the study of hepatitis B virus, mathematical models were used to explain interactions between hepatitis B virus and the human host in the absence and presence of interventions such as drug therapy and vaccines. This thesis …
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Laboratory investigation of low positive and discrepant HIV serology results
In our diagnostic virology laboratory, we test on average 1500 samples for HIV antibody/antigen each month, of which 0.6% produces problematic results. These problematic samples produce either weakly reactive screening and confirmatory results or, discrepant screening and confirmatory results. Both …
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Bioinformatics and Next Generation Sequencing: Applications of Arthropod Genomes
… as genomics, medical diagnosis, biotechnology, virology, biological systematics, forensic biology, and anthropology. Taken together, it has offered us brilliant insights into life sciences. Most of the work presented in this thesis describes NGS applications on genome assembly, genome …
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HIV/AIDS in South Africa : Towards a New Paradigm
… severity resulting in inevitable death. Virology identified the virus that is the infectious agent and provided explanations of how it had its effect on the host, reproduced and was transmitted. Influenced by the early association of AIDS with homosexuals, the social construction of …
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Design of a large-scale virus capsid model for educational use
… of many viruses, it is important to virology. A small icosahedral virus capsid consists of 60 identical proteins. Larger capsids are formed by adding quasi-equivalent proteins, with 60 copies of each unique protein. Our model calls for the creation of an injection mold for one unique …
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Arenaviruses: the Role of Antigen Presenting Cells (APC) in Persistence and Immunopathology
… discoveries in the field of immunology and virology; for example, understanding the role of the major histocompatibility complex. Though the LCMV model has been a critical player in the field of immunology and virology, most of the data from the model are from bulk analyses and made use of …
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Description of interactions of Ebola virus with a putative reservoir species using next-generation sequencing
… an extremely powerful and flexible tool in virology over the past decade as new library preparation techniques have been developed that permit the selective sequencing of small RNAs, and the characterization of entire viral populations at incredible levels of detail. For this work, I …
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Novel Epidemics: Contagion and Metaphor in US Literature
… biopolitics, literary studies, epidemiology, and virology in order to describe and analyze a new field of literary-cultural engagement with epidemic that reveals how epidemiology changed the way we read and think about US cultural and national identity.</p>
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Temporal gene expression and regulation in T4 phage
… for further exploration into molecular biology, virology, and biotechnology; our rich data set can be utilized by future studies to answer a diverse array of inquiries.
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Lentiviral Vector Engineering for High-Throughput Immune Profiling
… interaction. We have therefore used synthetic virology approaches to engineer a “lentivirus surface display” platform capable of screening complex antigen mixtures against the full complexity of the adaptive immune repertoire. In Chapter 2 of this thesis, we describe our molecular engineering …
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