Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 64 for “"viremia"”.
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Food insecurity at HIV diagnosis associated with subsequent viremia amongst adults living with HIV in an urban township of South Africa
… in care, hospitalization, mortality, and HIV viremia in an urban township of Kwazulu-Natal, South Africa. At the time of HIV testing, food security status was assessed using the Household Food Insecurity Access Scale (HFIAS), and people living with HIV were followed for at least twelve months. …
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Intranasal Immunization of Pigs with Porcine Reproductive and Respiratory Syndrome Virus like Particles Plus 2’, 3’ –cGamp Vaccigrade™ Adjuvant Exacerbates Viremia After Virus Challenge
… group demonstrated a significantly increased viremia at 7 and 10 DPC likely due to its ability to enhance the innate immune response and bring more immune cells for the virus to target. Interferon-alpha concentrations were also higher in the VLPs with adjuvant group, but there was only a …
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Yellow Fever: Role of Heterologous Flavivirus Immunity on Urban Emergence
… (DENV) and Zika (ZIKV) viruses, limits YFV viremia and transmission by Ae. aegypti. We infected cynomolgus macaques with DENV or ZIKV, then challenged them 6-9 months later with YFV. We then measured viremia and disease, and allowed Ae. aegypti mosquitoes to feed during peak macaque viremia. …
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Caracterización de viremias detectables en una población con VIH de un programa especial en Bogotá – Colombia entre abril de 2022 y abril de 2023
Introducción: Desde hace años, las viremias detectables en pacientes con VIH en tratamiento han generado preocupación por su progresión en algunos casos al fallo virológico, fracaso terapéutico y deterioro en la calidad de vida. Este estudio tiene como objetivo caracterizar las viremias detectables …
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Therapeutic Uses of Broadly Neutralizing Anti-HIV-1 Antibodies in Humanized Mice
… therapy (ART) significantly suppresses HIV-1 viremia in most infected individuals, but is incapable of curing disease. The major barrier to HIV-1 cure is a population of long-lived cells that harbor replication-competent provirus and are refractory to current therapies—termed the latent …
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Cytokine patterns in a comparative model of arenavirus infection: Implications for virulence and control of viral replication
… virus (P2) induces a mild disease with low viremia, while high passage Pichinde (P18) induces a severe disease with high viremia, ending in terminal shock. We hypothesized that severe disease would be associated with a suppression of potentially antiviral cytokines early in infection, and …
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Origin and Correlates of Viral Rebound in SIV-Infected Rhesus Macaques Following Discontinuation of ART
… anatomic sites, resulting in oligoclonal plasma viremia. Daily transcriptomic and proteomics profiling in peripheral blood following ATI identified early upregulation of pathways related to T cell signaling, cytokine responses, and metabolism prior to detectable plasma viremia, presumably …
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Modeling dengue viral infection, insect transmission and multiplex PCR in humanized mice
… to dengue virus infection as evidenced by viremia, and generation of dengue specific human IgM and IgG antibodies. Additionally, the presence of IgM and IgG that are capable of virus neutralization illustrated the functionality of the human immune system reconstituted in these mice. To …
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A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice
… and with mice dying at the peak of viremia. Here we describe a non mouse-adapted DEN2 virus strain (D2Y98P) that is highly infectious in AG129 mice (lacking interferon-a/? and -? receptors) upon intraperitoneal (ip.) and subcutaneous (sc.) administration. Infection with a high dose …
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Monitoraggio del BK virus nei pazienti trapiantati di rene
… della BK viruria per lo sviluppo della BK viremia e il suo possibile vantaggio per predire precocemente la BKVAN. Metodi: In 52 pazienti sottoposti a trapianto renale tra Novembre 2007 e Marzo 2009, è stata realizzata un¿analisi prospettica, per cercare la positività del BKV attraverso …
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Perfil sorológico e virêmico de suínos da raça Piau e linhagem comercial naturalmente infectados com o Porcine circovirus 2 em diferentes fases de produção
… totais por ELISA indireto e quantificação da viremia por PCR em tempo real. Os resultados demonstraram que, na idade de 3-8 semanas, os leitões da raça Piau soroconverteram mais precocemente em relação aos leitões da linhagem comercial e as porcas da raça Piau apresentaram menores níveis de …
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Genotypes and Clinical Characteristics of BK Virus in Kidney Transplant Recipients
… and 5 patients were shown to have BK viruria and viremia, respectively. . Eight viral strains were demonstrated to be genotype I, but the other 8 strains neither matched with the genotypes from I to IV, nor did they fit into any other variants identified in the Western countries. Of note, 3 of …
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Vector competence of Ochlerotatus trivittatus (Coquillett), Aedes albopictus (Skuse), and Culex pipiens (L) (Diptera: Culicidae) for West Nile virus
… primary reservoir of the virus and can develop viremias with titers higher than 1010.0 CID50s/ml. Culex species of mosquitoes are the primary amplifying vectors. Many species of mammals are also susceptible to WNV but develop viremias that seldom exceed 105.0 CID50s/ml. Mammals may play a …
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Generation and Characterization of Flavivirus Receptor-Binding Domain Mutants and Chimeras
… the kidney, despite generating a strong WNV-like viremia, suggesting a significant change in tissue tropism. The SLEV chimeras were particularly attenuated, with low peak viremia, suggesting a poor infection of early targets, despite strong WNV-like growth in vitro. The BAGV chimeras were …
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Pathogenesis and transmission of Venezuelan equine encephalitis virus
… and that differing infection routes affect the viremia and mortality of mice. Both the mosquito species and infection route used affected the amount of virus detected in the saliva. The amount of VEEV transmitted in vivo by mosquitoes during blood feeding was significantly less than in vitro …
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The pathogenesis of EHV1 in horses : novel insights from experimental inoculations and field situations
… tract, the virus spreads via a cell-associated viremia to target internal organs such as the uterus or the nervous system. Secondary replication of EHV1 in endothelial cells of these organs can result in late term abortion or nervous system disorders. Vaccination with the currently available …
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Entry of feline infectious peritonitis virus in blood monocytes
… most threatening. It causes a monocyte-derived viremia that leads to a progressive vasculitis and is mostly fatal for the infected cat. There is no effective treatment available. To address this matter, an improved knowledge of the pathogenesis of FIPV is needed. The process of viral entry is an …
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
… signs of diarrhea and other abnormalities nor viremia were observed in the pigs. Fecal shedding of the virus, however, occurred for 14 dpi even though those pigs had detectable antibodies in serum and oral fluid at the time of re-exposure, suggesting that prior infection can provide clinical …
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Pharmacokinetic-Pharmacogenetic-and-Pharmacodynamic Adherence Relationships in Cohort South African HIV Infected Children on Lopinavir-and Nevirapine-Based Regimens
… concentrations >1 mg/L reduced the risk of viremia (viral load >50 copies/mL) with about 40%, compared to children with LPV <1 mg/L. No association was found with percent adherence in this group. In 95 children on nevirapine post-randomization, nevirapine concentrations were not …
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Cross-protection and Potential Animal Reservoir of the Hepatitis E Virus
… as evidenced by fecal virus shedding and viremia, and the majority of pigs also developed IgG anti-HEV prior to challenge at 12 weeks post-inoculation. After challenge, viremia and fecal virus shedding of challenge viruses were not detected, suggesting that prior infection with a genotype …
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