Global ETD Search
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Showing 1 to 1 of 1 for “"viral population, diversity, yellow fever, attenuation, vaccine"”.
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Contributions of Structural and Non-structural Genes to the Attenuation of the 17D Vaccine
Live-attenuated 17D vaccine, developed to control Yellow Fever virus (YFV), was derived by serial passage of wild-type Asibi strain 176 times in mouse and chicken tissues. Despite the derivation of 17D over 75 years ago, the mechanism of attenuation is still poorly understood. The genomes of …