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Showing 1 to 5 of 5 for “"viral oncogenesis"”.
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The Art of Viral Oncogenesis: Lessons from Human Papillomavirus and Polyomavirus Transformed Cancers
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Tyrosine-Specific Protein Phosphorylation in Cells Transformed by Rous Sarcoma Virus or Stimulated by Mitogens
… involvement for this protein in the process of viral oncogenesis. Studies with a cell variant that is mitogenically unresponsive to TPA indicate that the phosphorylation of the 42K protein is not sufficient to stimulate DNA synthesis, although it may be a necessary condition. The phosphorylation …
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Regulation and function of the RNA-binding protein CELF1
… of CELF1 mediated mRNA decay may play a role in viral oncogenesis. To investigate this, we utilized a model of KSHV infection whereby HeLa cells were transfected with the oncogenic KSHV encoded GPCR. We found that the vGPCR caused CELF1 phosphorylation, likely in a MEK/ERK dependent fashion. We …
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Transcriptional and Translational Products of Avian Erythroblastosis and Avian Myeloblastosis Viruses
… AEV nonproducer cells were found to contain two viral related RNA species of 28 S and 21 S. Both RNA species contain the AEV unique sequences and the "strong stop" region of the viral genome, as detected by cDNA hybridizatin. In addition to the 28 S RNA, which is the genomic RNA of AEV, the 21 S …
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Strategies for Oncogenesis by Avian Leukosis Viruses
<p>The mechanism of oncogenesis by avian leukosis viruses (ALVs) was examined. ALVs are slowly transforming RNA tumor viruses that do not transform cells in tissue culture and that cause neoplastic disease only after a latent period of 4-12 months. ALVs generally induce widely disseminating B cell …