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Showing 1 to 3 of 3 for “"viral membrane fusion"”.
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Inhibiting HIV-1 entry : utilizing a transient intermediate of viral membrane fusion as a target for drug discovery
… cells. The first step of this process is the fusion of viral and cellular membranes, which allows the release of the viral contents into the cell. An envelope glycoprotein on the surface of the virus is responsible for fusion. It is usually composed of two subunits, a surface subunit that …
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Structure and Dynamics of AcrA, a Periplasmic Component of a Multidrug Efflux Pump
… classes of antibiotics. AcrB is the inner membrane (IM) pump that utilizes proton-motive force for the active transport, TolC is the outer membrane (OM) channel, and AcrA coordinates the actions of AcrB and TolC, so that substrates are expelled across the two membranes, bypassing the …
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FMF assay for assessing vaccine generated antibodies in a biomimetic manner
… of influenza hemagglutinin responsible for virus membrane fusion in the endosomes. In order to study Influenza vaccine response in a more biomimetic manner and overcome the deficiencies of the traditional functional assays, we developed a fluorescent membrane fusion assay (fMF). The assay uses …