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Showing 1 to 4 of 4 for “"viperin"”.
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The regulation and function of viperin during rhinovirus infection
… interferons and interferon stimulated genes. Viperin is one of the most highly upregulated interferon stimulated genes in rhinovirus infected airway epithelial cells. Viperin expression during viral infection has long been associated with direct antiviral effects across diverse viral infection …
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Biochemical and structural characterization of radical SAM enzymes Elp3 and viperin
Made available in DSpace on 2017-03-01T17:00:49Z (GMT). No. of bitstreams: 2 SELVADURAI-DISSERTATION-2016.pdf: 4094456 bytes, checksum: 0f8ac9e151d2ca2bcc0b86f28ca3e24e (MD5) LICENSE.txt: 4217 bytes, checksum: 97822b5b33afa06a1dd64bba5cddd611 (MD5) Previous issue date: 2016-08-19
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Biochemical and structural characterization of radical SAM enzymes Elp3 and viperin
… functions of two radical SAM enzymes: Elp3 and viperin. The eukaryotic Elongator complex is a large protein complex consisting of six Elongator proteins (Elp1-Elp6) and has been associated with several cellular processes and neurological diseases in humans. Of the six subunits, Elp3 is …
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The regulation of human airway epithelial expression of viperin by human rhinovirus
… have more frequent and severe viral infections. Viperin is a novel antiviral molecule that is induced in airway epithelial cells following HRV infection and that inhibits replication of HRV in these cells. We investigated the mechanisms of HRV-induced epithelial viperin expression, and the effect …