Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"ventromedial hypothalamus (VMH)"”.
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CHARACTERIZATION OF TRANSMEMBRANE PROTEIN 35 EXPRESSION: CONSIDERATIONS OF SEX AND OVARIAN HORMONES
… identified high expression of TMEM35 in both the ventromedial hypothalamus (VMH) and the limbic circuit of the mouse brain. Due to the known functions of these two regions, this pattern of expression indicates possible roles of this neuropeptide in social behavior and reward processing. …
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Possible role of the ventromedial hypothalamus in estrus termination following vaginocervical stimulation of the rat
… the present study investigated the role of the ventromedial hypothalamus (VMH) in estrus termination using sexually experienced ovariectomized female rats. First, females were administered subcutaneous injections of estradiol benzoate and progesterone before being assigned to 4 different …
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Role of Ceramide Accumulation in the Ventromedial Hypothalamus in Driving Systemic Metabolic Impairments During Obesity
… that during obesity ceramides accumulate in the hypothalamus, the region of the brain known to regulate many aspects of metabolism. As hypothalamic lipid metabolism is rapidly being established as a key player in whole-body metabolic homeostasis, we became interested in whether this ceramide …
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Exploring INSL5 and RXFP4 in the gut-brain axis and their potential role in feeding behaviour
… cells in the colon, DRG, NG and the ventromedial hypothalamus (VMH), a known feeding centre in the brain. Transcriptomic analysis of Rxfp4-expressing cells in the hypothalamus revealed enriched expression of multiple feeding-related neuropeptides and receptors. Circuit mapping of …
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Hypoglycemia-induced changes in glucose metabolism in the hypothalamus
… understood (3), but changes occurring in the ventromedial hypothalamus (VMH), a brain region that is responsible for initiating the counterregulatory response to hypoglycemia (4) is the most promising target. In the following studies, we utilized metabolomic (Chapter 2), transcriptomic …
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Mechanisms of intake depression in parasitised lambs
… experiment involved blocking the activity of the ventromedial hypothalamus (VMH) using mederantil, a compound with the active ingredient brotizolam, which blocks the diazapem receptor in the VMH. The second eXI)eriment utilised loxiglumide (CR1505) which antagonises the peripheral receptor of …
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Role of the ventromedial hypothalamus in control of innate defensive behaviours
… of the circuit controlling these behaviours. Ventromedial hypothalamus (VMH) is a key brain region for controlling responses to predators; it has been shown that inactivating the VMH can reduce defensive behaviours. Interestingly, activating the VMH output neurons (SF1+ cells) can produce a …
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Metabolic signalling and neuroendocrine stress responses in pregnancy
… in the lateral hypothalamic area (LPIA), ventromedial hypothalamus (VMH) and dorsomedial hypothalamus (DMH). Supraoptic and magnocellular PVN oxytocin responses to centrally administered NPY were reduced during late pregnancy. Endogenous opioids are involved in the attenuation of HPA axis …
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Mechanisms of hypothalamic regulation of food intake in birds
… central and peripheral neural signaling. The hypothalamus is responsible for integrating and processing these signals and thus is regarded as the regulatory center for balancing energy homeostasis. Eating disorders, such as compulsive eating behavior associated with obesity, and anorexia, are …
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A neural and behavioural investigation of aberrant feeding in animal models of autism spectrum disorder
… in the central amygdala (CEA), dorsomedial hypothalamus (DMH), ventromedial hypothalamus (VMH) and the nucleus accumbens (Acb). Excessive consumption palatable sucrose sucrose was was ameliorated in mutants by intraperitoneal administration of oxytocin (OT), a satiety promoting neuropeptide …