Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"vascular health"”.
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Determinants of vascular health in young people
… are independently associated with cardiovascular disease risk and/or mortality. Atherosclerosis begins in childhood and endothelial dysfunction is its earliest detectable manifestation. Endothelial dys/function can be quantified using flow mediated dilation (FMD). The primary aim of this …
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Lipoprotein(a) in vascular health: its role in inflammation, atherosclerosis, and arterial function
Η λιποπρωτεΐνη(α) [Lp(a)] είναι ένα μοναδικό σωματίδιο λιποπρωτεΐνης που παίζει σημαντικό ρόλο στην καρδιαγγειακή υγεία και νόσο. Δομικά, η Lp(a) αποτελείται από ένα κεντρικό σωματίδιο παρόμοιο με τη χαμηλής πυκνότητας λιποπρωτεΐνη (LDL), το οποίο είναι συνδεδεμένο ομοιοπολικά με μια γλυκοπρωτεΐνη …
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The effects of whole-diet interactions on vascular health and inflammatory and fatty acid status.
… dietary strategies that will contribute to healthy ageing. The NU-AGE project (EU FP7) aims to examine the impact of a year-long whole-diet intervention (including advice on intakes of the n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) on chronic low grade …
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The effect of freeze dried whole watermelon powder on endothelial function and vascular health in older adults
… of freeze dried whole watermelon powder on cardiovascular biomarkers and endothelial health. In a 16-week double-blinded, randomized placebo-controlled study design, 38 men and women between the ages of 45 to 79 years old consumed whole freeze dried watermelon powder or placebo powder (control). …
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The effect of vitamin K On vascular health and physical function in older people with vascular disease
… such as the increasing demand and expense on health and social care. Cardiovascular disease, prevalent in older people, goes hand in hand with declining physical function and new ways of tackling the burden this places on older persons, their carers and health services are …
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The impact of vascular calcification on ambulatory and central aortic blood pressure in a South African dwelling dialysis population : a clinical, radiological and pathophysiological study of vascular health in a young prevalent dialysis population in a developing country
In Sub-Saharan Africa, the prevalence of vascular calcification (VC) in CKD-5D is unknown. We undertook to determine the effect of ethnicity on VC, the risk factors for VC, the utility of abdominal X-ray (AXR) in predicting coronary calcium score (CCS) and the effect of VC on central aortic …
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Plasma nitrite reserve and vascular function before and after handgrip training in patients with heart failure
There is a direct relationship between vascular health and physical function. The controllers of this relationship are unclear, but appear to involve biomechanical and biochemical influences on the vascular wall. Purpose: The purpose of this dissertation was twofold: (1) to explore the relationship …
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ApoE, ApoER2, and the Regulation of Endothelial Cell Function
Cardiovascular disease risk is greater in individuals with the apolipoprotein E (ApoE) allele ApoE4 versus ApoE3, and this is not explained by differences in lipid profiles. A point mutant of the ApoE receptor ApoER2, ApoER2-R952Q, is also associated with greater cardiovascular disease risk, …
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The effect of soy isoflavone intake on cardiovascular disease risk factors - potential role of equol
… found in soybeans, may reduce the risk of cardiovascular disease (CVD). However, the current evidence is inconsistent. The capability to produce the isoflavone metabolite equol in 20-60 % of the population might underlie the benefits of isoflavone intake on vascular health. In a retrospective …
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Sex Differences In Endothelial FoxO1 Response To Nutrient And Oxidative Stress
Endothelial cells (ECs) are vital for vascular homeostasis, regulating blood flow, nutrient exchange, and immune responses. EC dysfunction contributes to diseases such as type 2 diabetes, atherosclerosis, and hypertension, with sex-specific differences in disease progression. Our lab previously …
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Thermal-based probe for testing endothelial dysfunction and possible implications for diagnosing atherosclerosis
… is a precursor to atherosclerosis. Thus, the vascular health of an individual can be assessed if endothelial dysfunction can be readily and unambiguously quantified. A thermal-based approach using temperature and blood perfusion measurements in conjunction with an arterial challenge has the …
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ULTRASOUND ASSESSMENT OF BRACHIAL ARTERY FLOW-MEDIATED DILATION FOLLOWING ACUTE KOMBUCHA TEA CONSUMPTION IN HEALTHY MEN
… tea consumption is inversely related to cardiovascular disease, and short-term ingestion can transiently improve endothelial function using percent change in flow mediated dilation (FMD%) as an index. Kombucha tea has many claimed health benefits, including the ability to improve endothelial …
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Prevalence of Hypertension Among Low-Income Individuals in Muscogee County Columbus, Georgia
… disparities influenced by systemic inequities, healthcare access, and chronic stress. Gender differences were modest, with females exhibiting a slightly higher prevalence (77.9%) than males (76.7%), potentially due to age-related hormonal changes post-menopause. Older adults (50+ years) …
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Nicotinamide Riboside Delivery Generates NAD+ Reserves to Protect Vascular Cells Against Oxidative Damage
The ability of vascular cells to withstand oxidative insults is critical to vascular health. NAD+, which drives poly (ADP-ribose) polymerase (PARP) and sirtuin (SIRT) reactions, can be compromised and strategies for overcoming this limitation in the vasculature do not exist. This study determines …
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Examining endothelial function in humans in vivo: improving guidelines and exploring novel measures
… and new measurement of endothelial function, and vascular health. The first part of this thesis focussed on the “old” flow-mediated dilation measurement, introduced in 1992, which relies on brachial artery vasodilation after a hyperaemic stimulus (e.g. after occlusion of a pneumatic cuff), and the …
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Exploring The Translational Clinical Value of Cerebrovascular Reactivity Assessments by Diffuse Correlation Spectroscopy
Cerebrovascular reactivity (CVR), i.e., the ability of cerebral vasculature to dilate or constrict in response to vasoactive stimuli, is a biomarker of vascular health and CVR quantification is considered an unmet clinical need. However, the value of addressing this unmet need is not clear. This …
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Ketosis Suppression and Ageing (KetoSAge): Suppression of ketosis negatively affects multiple biomarkers associated with chronic diseases and ageing
… decrease quality of life and youth-span. Cardiovascular disease, Alzheimer’s disease, cancer, type 2 diabetes mellitus, metabolic-dysfunction-associated steatosis liver disease, and fragility fractures are diseases of hyperinsulinaemia that reduce life and healthspan. Hyperinsulinaemia …
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Intermittent Standing and Prior Exercise as Strategies to Prevent Arterial Stiffening That Can Arise From Prolonged Sitting
<p>Prolonged sitting can cause adverse vascular responses, including elevations in aortic stiffness which might contribute to cardiovascular disease (CVD). Few studies have investigated the impact of intermittent standing and/or prior exercise as strategies to mitigate these deleterious vascular …
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Impact of Prolonged Sitting on Central Hemodynamics: Role of Intermittent Pneumatic Compression Therapy
… (3-6 hours) negatively impacts peripheral vascular health. Whether sitting similarly impacts central cardiovascular hemodynamics and vascular stiffness is unknown. <strong>Purpose: </strong>Determine if prolonged sitting increases central blood pressure, aortic pulse wave reflection and …
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EFFECTS OF PASSIVE STATIC STRETCHING ON MECHANICAL, NEUROMUSCULAR, AND CARDIOVASCULAR FUNCTION
… stretching (PSS) induces neuromuscular and vascular adaptations through both mechanical and neural mechanisms, influencing range of motion, muscle strength, and vascular health. While previous research has primarily focused on individual muscles or muscle chains, the regional (compartmental) …
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