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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 126 for “"vascular endothelial growth factor (VEGF)"”.

  1. Expression of Vascular Endothelial Growth Factor(VEGF), Vascular Endothelial Growth Factor Receptor-1(VEGFR-1), Hypoxic Induced Factor-1alpha(HIF-1α) mRNA in Papillary Thyroid Microcarcinoma(PTMC)

    윤, 태일2011

    … Angiogeneisis is essential process for tumor growth and metastasis. Vascular endothelial growth factor(VEGF) is major regulator of angiogenesis. Recently, the incidence of papillary thyroid microcarcinoma(PTMC) increased because of development in diagnostic modality. Several recent reports …

    ajou Repository record

  2. Experimental estimate of the diffusivity of Vascular Endothelial Growth Factor

    Núñez, Daniel AMassachusetts Institute of Technology2006

    The diffusivity of Vascular Endothelial Growth Factor (VEGF) is a number that is very important in determining the transport of VEGF. The transport of VEGF determines crucial processes such as angiogenesis and vasculogenesis. This study aimed at obtaining an estimate of the diffusivity of VEGF by …

    mit Repository record

  3. Reoxygenation of hypoxic coronary smooth muscle cells amplifies growth-retarding effects of ionizing irradiation

    Arab, Amina

    … doses of 4, 8 and 16 Gy using a 60Co-source. Vascular endothelial growth factor (VEGF) gene expression was dramatically suppressed in reoxygenated versus hypoxic HCSMCs independent of the radiation dose. Likewise, hypoxia induced factor 1alpha (HIF-1alpha)expression was suppressed in …

    freiburg-diss Repository record

  4. Effects of combination therapies on age-related macular degeneration

    Lo, DavidBoston University2013

    … The treatments explored in this paper are: anti-vascular endothelial growth factor (VEGF) drugs, photodynamic therapy (PDT) and steroids. All three require invasive eye procedures that carry their own risks. The possibility of more effective treatments by combining these therapies is being tested …

    bu Repository record

  5. Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro

    Fliedner, Anselm

    Die vorliegende Arbeit untersucht die Effekte von Vascular Endothelial Growth Factor (VEGF), Transforming Growth Factor-beta-1(TGF-beta-1), Interleukin-6 (IL-6), Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und Cortisol (bzw. Dexamethason) auf das humane Myokard. Um …

    freiburg-diss Repository record

  6. Cytotoxic Effects of Ruthenium Compounds on Human Cancer Cell Lines.

    Brown, Katie Beth2008

    … cytotoxic properties. In addition, levels of vascular endothelial growth factor (VEGF) production were tested in supernate from the cancer cells treated with various ruthenium-based compounds to determine whether or not the ruthenium-based compounds had an effect their VEGF production. Our …

    etsu Repository record

  7. The Effects of Angiogenic Growth Factors on Mesenchymal Stem Cell Proliferation and Differentiation to Vascular Cell Fates

    D'Angelo, William Anthony2018

    … surround and support blood vessels, and possibly endothelial cells, which form the blood vessel walls. In this study, we investigated the effects of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF), two of the best-characterized angiogenic factors, on MSC …

    usm Repository record

  8. Signalling and function of the small Rho GTPase RhoJ in endothelial cells

    Leszczynska, KatarzynaUniversity of Birmingham2011

    RhoJ is an endothelial expressed Rho GTPase, and its knock-down impairs endothelial cell (EC) migration and tubulogenesis, increases stress fibre (SF) and focal adhesion (FA) numbers. This work aimed to determine the intracellular localisation of RhoJ, identify its binding partners, test how it is …

    birmingham Repository record

  9. Examining physiological roles of adipose derived VEGF: Consequences in substrate availability and endurance exercise capacity in adipocyte specific VEGF deficient mice

    Zachwieja, Nicole J.2019

    Reducing vascular endothelial growth factor (VEGF) in adipose tissue alters adipose vascularity and metabolic homeostasis. We hypothesized that this would also affect metabolic responses during exercise-induced stress, and that adipocyte-specific VEGF deficient (adipoVEGF-/-) mice would have …

    wvu Repository record

  10. Lokale Therapie der Sauerstoff-induzierten angioproliferativen Retinopathie im Mausmodell : Small Molecule Receptor Tyrosine Kinase Inhibitors

    Junker, Bernd

    Das Glykoprotein Vascular endothelial Growth Factor (VEGF) ist einer der Hauptmediatoren der Angiogenese und zählt zu den wichtigsten Faktoren in der Pathogenese der angioproliferativen Retinopathie. Die Wirkung von VEGF wird über spezifische Rezeptoren vermittelt, die zur Familie der …

    freiburg-diss Repository record

  11. Genetic Association Study of Osteoporotic Vertebral Compression Fractures in Postmenopausal Women

    정, 영선2011

    Vascular endothelial growth factor (VEGF) is involved in bone formation through its role in angiogenesis. VEGF is also known to promote the healing of fractures and hyperhomocysteinemia is associated with the risk of skeletal health problems, such as osteoporosis, low body mineral density, and …

    ajou Repository record

  12. Adipogenesis and angiogenesis : roles in tissue engineering and glucose metabolism

    Tam, JoshuaMassachusetts Institute of Technology2009

    … organ, producing and secreting various enzymes, growth factors, cytokines, and hormones. Both of these functions require ample access to circulating blood. Many aspects of angiogenesis during adipose tissue expansion remain poorly understood. Adipocytes produce a large variety of molecules …

    mit Repository record

  13. Inhibition of progestin-induced VEGF in mammary cancer by curcumin and 2-methoxy estradiol and their potential role as anti-angiogenic & chemopreventive compounds

    Carroll, Candace E.University of Missouri--Columbia2009

    … release, from breast tumor cells, of vascular endothelial growth factor (VEGF), a potent angiogenic growth factor. In the present study I show that curcumin, a turmeric root derivative, and 2-methoxyestradiol (2ME2), a natural metabolite of estradiol, effectively inhibit …

    missouri Repository record

  14. OVEREXPRESSION OR REDUCED BIOAVAILABILITY OF VEGF DURING MOUSE POST-NATAL INTESTINAL DEVELOPMENT ALTERS THE PROLIFERATION OF INTESTINAL STEM CELL PROGENITOR CELLS

    Garcia Mojica, Salvador2014

    <p>Vascular Endothelial Growth Factor (VEGF) is a highly conserved ligand that is involved in the regulation of angiogenesis and vasculogenesis, however, alternative roles of the ligand have been emerging. Organisms such as jellyfish and <em>Drosophila</em> contain VEGF homologs, yet they do not …

    csusb Repository record

  15. Synthesis and bio-pharmacological activity of antisense phosphatidyl-oligonucleotides

    GRECO, VALENTINAUniversità degli studi di Catania2011

    … all having the antisense sequence against the Vascular Endothelial Growth Factor (VEGF) gene, but differing from each other in their phosphatidyl moiety. This consisting of different fatty acyl residues, such as myristoyl, palmitoyl and stearoyl as well. The newly synthesized …

    catania Repository record

  16. Polymorphisms in the Flt1 gene and their relation to expression of the secreted Flt1 variant

    Ajlouni, Burouj KayedVirginia Tech2009

    Vascular endothelial growth factor (VEGF) is a potent angiogenic agent. VEGF activates its biologic responses through two cell-surface receptors, Flt1 and Flk1. In addition to the transmembrane form of Flt1, the Flt1 gene also encodes a secreted, truncated form of the receptor (sFlt1) translated …

    vt Repository record

  17. Common Signaling Elements in Response Pathways Activated by the Endothelial Survival Factors VEGF and Insulin

    Wang, Amanda CyphersVirginia Tech2008

    … mellitus. At the cellular level, dysfunction of vascular endothelial cells is often associated with diabetic conditions. Multiple agents maintain the endothelium, including vascular endothelial growth factor (VEGF), an endothelial cell mitogen/survival factor, and insulin, which has …

    vt Repository record

  18. A Study Of The Molecular Genetics Of Renal Cell Carcinoma In Man

    Ollerenshaw, Martin2003

    … the expression levels of hypoxia inducible factor 1-α (HJF-lα), glucose transporter one (GLUT-1), and vascular endothelial growth factor (VEGF) isoforms 165 and 189 mRNA in patients with renal cell carcinoma (RCC). Patients with RCC underwent radical nephrectomy at Derriford Hospital, …

    plymouth Repository record

  19. Uncovering Molecular Targets to Overcome Immunosuppression In Non-Small Cell Lung Cancer With Acquired Tki Resistance

    Patel, Sonia A, <p>https://orcid.org/0000-0002-6494-7872</p>2023

    … therapeutic agents, such as epidermal-like growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) or monoclonal antibodies targeting vascular endothelial growth factor (VEGF/R), can effectively inhibit upregulated signaling pathways driving tumorigenesis in NSCLC and many other …

    uthsc Repository record

  20. Protein Semi-Synthesis in Vivo

    Stankiewicz, Izabela Giriat

    … tag, and an imaging moiety. Specifically, vascular endothelial growth factor (VEGF) was ligated with a 6xHis tag and a synthetic high affinity <sup>99m</sup>Tc chelator. Following protein semi-synthesis, the <sup>99m</sup>Tc was incorporated into the chelator and the …

    rockefeller Repository record

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