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Showing 1 to 5 of 5 for “"vascular aging"”.

  1. A Tissue-Engineered Blood Vessel Model for Vascular Aging

    … have identified strong correlations between aging and the development of atherosclerosis. In particular, endothelial cell senescence is implicated in age-related changes in vasoreactivity. Oxidative stress is considered the primary source of endothelial cell (EC) senescence in vivo. EC …

    duke Repository record for A Tissue-Engineered Blood Vessel Model for Vascular Aging (opens in a new tab)

  2. The relation between sex, age and vascular function in the Framingham Heart Study

    … is a key modulator of the development of cardiovascular disease. Prior studies in selected samples have suggested that the association of age and vascular function may vary between men and women. To investigate the sex-specific patterns of this association, we utilized non-invasive vascular

    bu Repository record for The relation between sex, age and vascular function in the Framingham Heart Study (opens in a new tab)

  3. The structural and functional changes of blood vessels during aging

    The vascular adventitia is recognized as a dynamic mediator of vascular structure and function, yet its role in aging is not understood. The purpose of this thesis was to examine the age-related changes of the vascular adventitia and determine the underlying mediators responsible. Male …

    brock Repository record for The structural and functional changes of blood vessels during aging (opens in a new tab)

  4. Aging Effects on Arterial Mechanics and Matrix Remodeling

    … or amount through matrix remodeling. Aging causes elastin fragmentation and degradation which changes the elastin:collagen protein ratio and increases the arterial stiffness. More pressure is required to distend the arterial wall to maintain normal function, so a pathological …

    wustl Repository record for Aging Effects on Arterial Mechanics and Matrix Remodeling (opens in a new tab)