Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2532 for “"vascular"”.
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Prolylcarboxypeptidase protects from vascular dysfunction and promotes vascular repair
… The following studies characterize the vascular phenotype of the PRCP-deficient (PRCPgt/gt) mouse. Compared to wildtype animals, PRCPgt/gt are hypertensive and demonstrate faster times to induced arterial thrombotic occlusion. PRCPgt/gt have increased levels of vascular reactive oxygen …
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Mineralocorticoid receptor involvement in vascular dysfunction associated with vascular injury
… signaling has recently been implicated in cardiovascular dysfunction associated vascular injury. Specifically, MR blockade has been shown to treat coronary microvascular dysfunction in obesity and has been implicated in the regulation of capillary density in ischemic conditions. The fundamental …
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The Vascular Characteristics
… The purpose of this study was to investigate the vascular characteristics of melasma and expression of VEGF, a major angiogenic factor, and its receptor in lesional melasma skin. MATERIAL AND METHODS: Erythema intensity was quantified by the increase of the a* parameter using a colorimeter. 2 mm …
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Vascular Injury In Col3A1+/- Mice Model of Vascular Ehler-Danlos Syndrome
<p>Vascular type of Ehlers-Danlos Syndrome (vEDS) is an inherited cardiovascular disease affecting the middle to large sized arteries, with an incidence rate of 1/5000. vEDS patients also show a significant phenotype of easily bruised skin, indicating aberrant wound healing and injury repair …
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Runx2 and Vascular Calcification
Complications arising from vascular calcification, the inappropriate deposition of calcium phosphate crystals in the vasculature, have become more evident in recent years as human longevity has increased. Arterial calcification is frequently categorized as two types, depending on where it occurs: …
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Nutrition and vascular function.
… the risk of atherosclerosis through altering vascular function. Modification of dietary intake and weight loss can ameliorate these risk factors and may impede the development of atherosclerosis. CVD risk can be assessed by measurement of both traditional e.g. lipid levels, glucose and blood …
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Cyclic stretch-mediated release of vascular endothelial growth factor by vascular smooth muscle cells : a role in improved vascular graft patency
… phosphorylation in response to cyclic stretch in vascular cells, the effect of cyclic strain on the KDR-mediated endothelial response to locally-released VEGF was also investigated. Low passage number bovine aortic SMC and EC were plated on collagen-coated elastomer plates and subjected to 10% …
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A Vascular and Non-Vascular Flora of the McGee Creek Watershed, Mono County, California
… better understand the flora, 2860 collections of vascular and non-vascular plants were made across the watershed in 2024 and 2025, and 187 specimens collected before 2024 were examined. In total, the flora of the McGee Creek watershed includes at least 970 species (774 vascular, 196 non-vascular) …
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Risk Factors for Vascular Dementia
… over the age of 65. Alzheimer's disease and vascular dementia are the most common forms of dementias. A number of studies have implicated cardiovascular risks as important factors in the development of dementia. These risks include high-risk behaviors such as smoking and risks related at …
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Modeling vascular smooth muscle contraction
… framework to investigate issues regarding vascular smooth muscle contraction. The overall structure of this thesis consists of (1) a model of single vascular smooth muscle cell membrane electrophysiology, contractile system kinetics and cell mechanics; (2) a model of signal transduction of …
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Vascular remodelling in malignant hypertension
… pathogenesis. However the principal pathology is vascular remodelling of resistance vessels, termed fibrinoid necrosis, which causes ischaemic end-organ injury. Cardiovascular disease is the leading cause of mortality in western society and typically the consequence of atheromatous and/or …
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Investigating pulmonary vascular B cells
… of neutrophils which remains adherent to the vascular endothelium for extended periods of time and exhibits marginated behaviour. While pulmonary vascular neutrophils are important in the acute immune response of the lung, they tend to exhibit an aged and pro-inflammatory phenotype. While …
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Electrospun Tissue Engineered Vascular Grafts
ePTFE and Dacron vascular grafts are successful in large diameter applications but provide poor outcomes in small diameter (<6 mm) applications. Occlusion, poor cell ingrowth and a mismatch of compliance compared to the native vessel, cause failure to the current synthetic grafts. Spontaneous …
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Vascular endothelial cell-surface proteoglycans
… cell layers of normal ("cobblestone") bovine vascular endothelial cells in culture. Treatment of the parent molecules with dithiothreitol caused their complete cleavage and permitted the subsequent separation of the larger and smaller subunits on Sepharose CL4B columns. Removal of …
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Electrospun Tissue Engineered Vascular Grafts
ePTFE and Dacron vascular grafts are successful in large diameter applications but provide poor outcomes in small diameter (<6 mm) applications. Occlusion, poor cell ingrowth and a mismatch of compliance compared to the native vessel, cause failure to the current synthetic grafts. Spontaneous …
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Pericytes in Early Vascular Development
… and pericytes during development, we observed vascular morphology in three and four dimensions, as well as the genetic and molecular mechanisms underlying how these cells are recruited and interact in several experimental models. Thus, to thoroughly analyze the morphology of these vessels, we …
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Role of SFLT-1 in vascular regulation in pregnancy and its effect on fetal vascular programming
Various angiogenic growth factors, such as the vascular endothelial growth factor (VEGF) and placental growth factors (PlGF), have been shown to play an important role in the vascular physiologic changes occurring during pregnancy; therefore inhibition of these factors by a circulating scavenger …
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Tratamento da necrose vascular de Tálus
A necrose avascular (NAV) de Tálus decorre de lesão isquêmica que seja intensa ou prolongada o suficiente para causar necrose. O tálus apresenta uma grande área de cartilagem articular e não possui nenhuma inserção muscular ou tendínea, isso contribui para que ele tenha um sistema de suprimento …
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DRUG ELUTING TISSUE ENGINEERED VASCULAR GRAFTS
Electrospun Tissue Engineered Vascular Grafts (TEVG) have been synthesized with variable success. TEVG ≤5mm in diameter have had limited success due to poor patency outcomes with high rates of restenosis secondary to a phenomenon called Intimal Hyperplasia (IH). We have performed previous animal …
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