Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"varicella"”.
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The role of natural killer cells in control of varicella zoster virus infection
Varicella zoster virus (VZV) is a globally important virus with significant health and economic impacts. Although primary VZV infection is often perceived as a mild childhood illness, VZV infection is lifelong and reactivation of the latent virus in the elderly and immunocompromised population …
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Childhood varicella vaccination: an evaluation of clinical effectiveness, safety and cost effectiveness in Ireland
Background Varicella (chickenpox) is a common, highly contagious, vaccine-preventable disease that mainly affects children. Although typically mild, serious complications requiring hospitalisation do occur. Varicella is also associated with significant productivity loss mainly due to absence from …
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The utility of CSF PCR in central nervous system Varicella zoster infection in HIV
… cohort of HIV positive individuals with positive varicella zoster virus (VZV) positive cerebrospinal fluid PCR. Methods: Patients in the NHLS database at Groote Schuur Hospital with positive CSF VZV PCR who were also HIV co-infected and whose folders were available for clinical review were …
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Epidemiology and modelling to support the routine infant immunisation programme in England.
… and the potential introduction of a universal varicella vaccine. Two dynamic transmission models were developed and applied to evaluate these issues. The first model assessed the consequences of withdrawing the Hib/MenC vaccine from the infant schedule, revealing that teenage MenACWY …
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Development of protein microarrays for the investigation of host-pathogen interactions
Varicella-Zoster virus (VZV) is a human herpesvirus (causing chickenpox and shingles upon reactivation) whose diagnosis is particularly important in pregnancy and immunocompromised patients. Current sérodiagnostic assays are either based on crude whole cell lysates or glycoprotein preparations …
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Mathematical modeling for epidemiological inference and public health support
… individual-based stochastic model of Varicella Zoster Virus (VZV) transmission, whose main novelty is the inclusion of realistic population dynamics over the last century. This chapter represents an attempt to answer the need pointed out by recent studies for a better understanding of …
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Economic evaluations of vaccines in Canada: Exploring the epidemiologic and economic impact of chickenpox vaccine strategies in Canada using an agent-based model
… Chickenpox is a childhood disease caused by varicella-zoster virus (VZV), which can reactivate as shingles in adulthood. While natural waning of VZV cell-mediated immunity (CMI) can lead to shingles reactivation, one theory posits contact with a shingles or chickenpox case may boost an …
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DISSECTION OF HOST-VIRUS INTERACTIONS IN THE HUMAN CENTRAL NERVOUS SYSTEM
… simplex virus-1 (HSV-1), Monkeypox virus (MPXV), Varicella zoster virus (VZV) and Influenza A viruses (IAV). Our comparative virology approach demonstrated a susceptibility and permissiveness to herpesvirus infection, while in contrast neurons did not show any productive infection to either IAV or …
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MUTATION OF REGNASE-1 CAUSES PRIMARY IMMUNODEFICIENCY ASSOCIATED WITH AUTO-INFLAMMATORY DISEASE
… and had several episodes of severe varicella zoster virus (VZV) infections, including pneumonia and meningitis. Immunologically, the patient had increased IgM and IgG levels, absent IgA, low specific antibodies and multiple auto-antibodies, including anti-Interferon- antibodies. …
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Bell's Palsy - Medical Treatment and Influence of Prognostic Factors
… of viruses such as Herpes simplex type-1 or Varicella zoster may cause Bell’s palsy. The natural course is favourable but at least 30% of patients will suffer sequelae such as residual paresis, synkinesis and/or contracture. The most commonly used medical treatment to reduce sequelae has been …
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Proteomic analysis of the sorting machineries involved in vesicular traffic between the biosynthetic and endosomal compartments
… regulate the intracellular trafficking of the varicella-zoster virus glycoprotein I, a protein localized in the trans-Golgi network. Embo J. 15:6096-110. Bonifacino, J.S., and B.S. Glick. 2004. The mechanisms of vesicle budding and fusion. Cell. 116:153-66. Eskelinen, E.L., Y. Tanaka, and P. …