Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 76 for “"valency"”.
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Biomolecular Condensates Through a Computational Microscope Design, Mechanisms and Implications
… in diverse systems. My findings show that valency is a master regulator of phase separation, influencing both the propensity for condensate formation and the material properties of the resulting coaservates. By examining prion-like domains, I show how specific residue identities modulate …
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Compositional Control of Phase-Separated Cellular Bodies
… large polymers of the multivalent scaffolds. Low valency client molecules partition differently into these structures depending on the stoichoimetric ratio of the scaffolds, with a sharp switch in recruitment across the phase diagram diagonal. Composition can switch rapidly through changes in …
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A Lexical Functional Grammar Account of Spanish Weak Dative Pronominals
… where they are not lexically specified in the valency of the verb, the so-called non-selected datives. The analysis of the dative in ditransitive constructions is twofold. We claim that the distribution of the dative in such configurations has semantic and syntactic implications. The presence …
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The effect of cadmium on some enzymes in the developing chick embryo
… Atomic number 48; atomic weight 112.4; valency 2 and specific gravity a.?. The metal melts at 321°C and boils at ?65°c, and is remarkably volatile for a heavy metal. Its volatility has constituted a special industrial hazard since its b.p. is below the melting point of copper (1083°C), …
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A grammar of Chukchi
… agency relationships. Chapter 11 describes valency, surveying transitivity types and describing the valency changing and rearranging derivations available in the language, including antipassive, causative and applicative. Incorporation and compounding by verbs is discussed in chapter 12. …
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A grammar of Chukchi
… agency relationships. Chapter 11 describes valency, surveying transitivity types and describing the valency changing and rearranging derivations available in the language, including antipassive, causative and applicative. Incorporation and compounding by verbs is discussed in chapter 12. …
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Study of a Transferrin Receptor Brain Shuttle for the Delivery of Nanobodies Against GABAA Receptors
… across unconjugated 8D3 formats, regardless of valency, and was reduced by targeted mutations of the complementarity-determining regions (CDRs). TfR expression at the cell surface was also investigated to better understand the mechanistic effect of 8D3 valency, indicating drug-induced changes …
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Exploring multivalency and chemical modifications in the development of anti-PD-L1 peptide inhibitors for cancer immunotherapy
… anti-PD-L1 peptides and exploring how valency influences the blocking efficacy, potency, stability, anti-cancer effect, and tumor penetration. We also aim to optimize the sequence and structure of TR3 to develop more potent and stable TR3 derivatives. This involves modifying sidechains …
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A grammar of the Neverver language of Malakula (Vanuatu)
… either inherently transitive or intransitive; valency increase is achieved with suffixation, while valency decrease can be achieved with reduplication. Reduplication is common in the corpus and typically serves as a marker of low transitivity. In keeping with the basic constraint on syllable …
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Investigating the controlled oxidation of manganese oxides with the Brownmillerite structure
… mixed manganese valence. Significant mixed valency in manganese has not previously been reported in Sr2MnGaO5, Ca2MnGaO5 or SrCaMnGaO5. Oxidation of Sr2MnGaO5, nominally Mn3+ to Sr2MnGaO5.5, nominally Mn4+, occurs rapidly without intermediates, whereas both Ca2MnGaO5 and SrCaMnGaO5 show no …
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Engineering periodic short hairpin RNA delivery systems for enhanced therapeutic efficacy
… siRNA delivery systems, particularly as the low valency and high rigidity of siRNA make it difficult to condense into stable nanoparticles. Here we engineer the siRNA cargo to make it more amenable to stable encapsulation by using a polymeric form of siRNA, or periodic short hairpin RNA …
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A study of the nature and origin of the minialbumins to be found in cadmium-poisoned animals
… of ata:nic number 48, atomic weight 112.41 and valency 2, is a soft 'White lustrous metal belonging to the second sub-group of the Periodic Table. It has a boiling point of 768°c, melting point of 321°0, is remarkably volatile for a heavy metal, and exists naturaly as a mixture of eight …
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Exploring Critical Vehicle Parameters for the Design of Multitargeted Nanoparticles for Cancer Specific Gene Delivery
… model was built to explore how the affinity and valency of dual-ligand liposomes affect the binding and selectivity of delivery to cells with various receptor expression. α5β1 and α6β4 integrin expression levels were then quantified on 20 different cell lines to identify appropriate model cells …
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Metal-ligand redox interaction in the multielectron chemistry of porphyrinogen coordination compounds
… of ligand-based two-electron mixed valency (Chapter III). Dianionic zinc porphyrinogen reacts with carbon dioxide, and neutral zirconium(IV) porphyrinogen with dioxygen. Two zirconium porphyrinogen units can carry a water molecule as an oxo bridging the metals and two protons on the …
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Towards ultrahigh-throughput phenotypic screening using microfluidic droplets and functionalised polyacrylamide beads
… (Chapter 2). I explore the impact of construct valency on the potency of apoptosis induction for two TRAIL-receptor agonists, observing that potency is strongly dependent on agonist valency and therefore likely also on microdomain formation (‘lipid rafting’) for TRAIL-receptor. We use …
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Studies in Septuagint Leviticus: Linguistics, Tradition, and Lexical Choice
… introductory chapter, chapter 2 shows that the valency of Hebrew verbs (in this instance qṭr) is an important tool for the analysis of translation technique. In this case, discovering and understanding the deviations by Greek translators in Lev 3:11 and 16a. Chapter 3 provides further analysis …
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Bildung und Nutzung multinuklearer Titanocenkomplexe mit N-heterocyclischen Brückenliganden
… between titanium centers of different valency as well as the transfer of concepts broadly applied in the field of mixed valence chemistry of late transition metal complexes. In combination with the chemical oxidation reactions, the redox behaviour of the trinuclear assembly has been …
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A study of the pH-dependent charge of a selection of highly weathered humic soils
… with organic matter and also competes with lower valency cations for exchange sites, in which way it interferes with the measurement of CEC in soils. Variation of charge with pH has important environmental implications, e.g. groundwater contamination with heavy metals as the soil becomes less …
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