Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"vaginal microbiome"”.
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Characterization of the vaginal microbiome in pregnancy
The vaginal microbiome plays an important role in women's reproductive health. Imbalances in this microbiota are associated with bacterial vaginosis, increased susceptibility to sexually transmitted infections, and negative reproductive outcomes. The causes of such variations, however, are poorly …
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The Vaginal Microbiome Related to Reproductive Traits in Beef Heifers
… beef operation is reproduction. In the human vaginal microbiome, dominance by Lactobacillus is a sign of reproductive health and fitness. In other species (non-human primates and ewes), Lactobacillus is found in low amounts and dominators of these microbial communities are considered to be …
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The association between the oral and vaginal microbiome of young South African women
… of healthy bacterial communities in the vaginal and oral microbiomes respectively. Both BV and PD are associated with an increased risk of preterm labour and negative birth outcomes, yet it is unknown whether PD and BV are independent risk factors or may be interrelated. Understanding the …
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Determination of factors affecting the community structure of Gardnerella spp. in the vaginal microbiome
… spp. are a hallmark of bacterial vaginosis – a vaginal dysbiosis characterized by the shift from a lactobacilli dominated vaginal microbiome to a diverse microbiome composed of many aerobic and anerobic bacteria. Gardnerella spp. are diverse both phenotypically and genotypically and likely …
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A metagenomic approach to understanding the relationship between the vaginal microbiome and women’s reproductive health
Vaginal microbes exert a strong influence on women's reproductive health. Perturbations in the vaginal microbiome have been associated with serious sequelae, such as bacterial vaginosis (BV) and pregnancy complications. The etiology of BV is multifactorial. To gain a mechanistic understanding of …
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Changes in vaginal microbiome of beef cows enrolled in estrous synchronization protocols and its relation to fertility
… that of cycling cows. Supplementation of P4 intravaginally with the use of a controlled internal drug release device (CIDR) improves cycle induction when compared to oral administration of P4. Vaginitis has been reported as a side effect to CIDR use in cattle, which raises concerns about its …
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Unraveling the Microbiome Connection: Exploring the Nexus of Endometriosis, Anxiety, and Dysbiosis
… research suggests that alterations of the microbiome may play a key role in both endometriosis and anxiety. We hypothesized that individuals with endometriosis and co-occurring anxiety will exhibit differences in self-reported mental health symptoms, endometriosis/pelvic pain symptoms, and …
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Induction of metronidazole and clindamycin resistance in gardnerella vaginalis
… is known to be the most common polymicrobial vaginal disorder in females of childbearing age. It is characterised by a change in the healthy vaginal microbiome, from an environment dominated by hydrogen-producing lactobacilli, to the overgrowth of opportunistic pathogenic bacteria particularly …
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CRISPR immune diversity in simulated and natural microbial populations
… When these communities are a part of the human microbiome, these interactions can also have significant impacts on the health of the human host. The CRISPR adaptive immune system is one of the ways in which microbes defend against viral infection, and it also holds a record of acquired immunity, …
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Phylometagenomics: a new framework for uncovering microbial community diversity
… scale. Finally, using 16S data from the Human Vaginal Microbiome Project, gener- ated here at VCU under the umbrella of the overall NIH HMP initiative, I give examples of the quality control, analysis and visualization pipeline that I developed to support the efforts of this project. In …
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The Role of Microbial Diversity in Female Reproductive Health: An Analysis of the Microbiome's Influence on Pregnancy Outcomes in Postparturient Mares
… pre-term birth. Blood, oral, fecal, uterine, and vaginal samples were collected from 58 postparturient mares by attending veterinarians at Hagyard Equine Institute in Lexington, KY, within 24-36 hours of foaling and before uterine lavage/infusion. Expected due date and date of delivery was noted …
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Characterisation of vaginal Prevotella strains from a cohort of South African adolescent girls and young women with and without bacterial women with and without bacterial vaginosis
… (BV), is characterised by a dysbiosis in the vaginal microbiome, and frequently associated with abundance of the genus Prevotella. Prevalence of BV is particularly high in sub-Saharan Africa and comprehensive characterisation of South African BV-associated bacteria is vital for BV management …
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Tiny Can Be Big: The Contribution of Microbial Extracellular Vesicles to Host-Pathogen Interactions
The human vagina hosts a microbiome formed by dense numbers of diverse bacterial species which can be categorised based on their species diversity. Despite the variation, the low-diversity communities (i.e. a dominant single species of Lactobacillus) is understood to represent the microbiota of …
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Diversity of vaginal microbiota associated with bacterial vaginosis and the impact on pregnancy outcomes in HIV-infected and uninfected women.
The composition of vaginal microbiota in pregnancy is important as it may influence susceptibility to adverse pregnancy outcomes. Dysbiosis of the vaginal microbiota caused by the replacement of protective resident microorganisms such as Lactobacillus spp. by anaerobic bacteria is known as …
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Prenatal stress, the placenta and maternal microbial transmission; implications for health and disease
… prenatal distress on the maternal and infant microbiome. This study yielded a final cohort off 111 nulliparous pregnant women that were recruited from the IMPROvED consortium at CUMH. Women enrolled in SMArTI completed distress questionnaires and provided saliva and fecal samples in the second …
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Effect of progestin-based hormonal contraceptives on genital inflammation and Th17 cell activation in adolescents at high risk for HIV infection
… combined oral contraceptive pills (COCPs) on the vaginal microenvironment of the FRT in AGYW was investigated as this relates to HIV risk, with particular focus on cervical Th17 cells and their related cytokines (Th17- related cytokines). Methods: One hundred and thirty HIV-negative adolescent …