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Showing 1 to 2 of 2 for “"vaccine strains RB51"”.
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Unraveling the host innate immune response to a respiratory model of Brucella abortus
… Currently, there are no efficacious Brucella vaccines for humans available. Very few studies have focused on identifying protective vaccines against respiratory exposure. Protection by B. abortus rough vaccine strains RB51 and RB51SOD is through strong CD4⁺ Th₁ and CD8⁺ Tc₁ adaptive immunity. …
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The ability of TLR agonists to upregulate Brucella abortus strain RB51 mediated protection in a murine respiratory model
… research is to generate a safe and effective vaccine for humans. Brucella abortus strain RB51, approved for use in cattle, provides protection by initiating a strong T-helper 1 (Th1) type response is a candidate vaccine. Based on a model for aerosol exposure mice were vaccinated intranasally …