Global ETD Search
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Showing 1 to 2 of 2 for “"vOTU"”.
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Biophysical Characterization of the vOTU Proteases from the CCHF and Dugbe Nairoviruses
… the ovarian tumor domain protease superfamily (vOTU) from nairoviruses, and the structural reasons for their specificities. The vOTU from the Crimean-Congo Hemorrhagic Fever Virus (CCHFV) has been implicated in the down-regulation of the innate immune response through its ability to cleave …
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Species Preference of Viral Deubiquitinating Proteases Toward ISG15 Through Structural and Enzymatic Characterization
… expressed by a range of RNA viruses. Viral OTUs (vOTUs) are found in nairoviruses such as Crimean Congo Hemorrhagic Fever virus (CCHFV), Nairobi sheep disease virus (NSDV), the Erve virus (ERVEV), and the Dugbe virus (DUGV), as well as in the areterivirus Porcine Reproductive and Respiratory …