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Showing 1 to 2 of 2 for “"vGlut1‑pHluorin"”.
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Biochemistry and physiological role of otoferlin
… vitro zu testen.Zusätzlich etablierten wir den pHluorin-basierten optischen Test der Exozytose in IHZ. Wir exprimierten pHluorin gekoppelt an den vesikulären Glutamat-Transporter 1 (VGLUT1). PHluorin ist eine pH-Wert abhängige GFP-Variante, die bereits in Neuronen verwendet wird. Seine …
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Novel Optical Tools to Investigate Presenilin Control of Neurotransmission
… in regulating neurotransmission. We utilized vGlut1-pHluorin, a pH sensitive analog of GFP tagged to a synaptic vesicle protein, that allows for reporting of synaptic vesicle cycling. These experiments found evidence that Presenilins do control neurotransmission and that they do so by …