Global ETD Search
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Showing 1 to 5 of 5 for “"uterine fibroid"”.
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Giving birth to a new approach: a retrospective comparison of radiation safety parameters between transradial and transfemoral approaches for uterine fibroid embolization at Groote Schuur Hospital, South Africa
Background: Uterine artery embolisation (UAE) is a recognised minimally invasive, effective and fertility preserving treatment option for patients with symptomatic uterine leiomyomas. The conventional transfemoral access (TFA) in UAEs remains the method of choice for the majority of South African …
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Novel Effects of Simvastatin on Uterine Fibroids
Uterine fibroids (also known as leiomyomas) represent a common gynecologic problem with a significant medical and economic burden. Unfortunately, no satisfactory long-term medical treatment is currently available. Statins are drugs commonly used for the treatment of high plasma cholesterol levels. …
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Multiple testing procedures for complex structured hypotheses and directional decisions
… procedure is developed in the context of uterine fibroid gene expression data (Davis et al., 2013). The main question of interest that arises in this research is to discover genes associated with various stages of tumor progression, such as tumor onset, growth and development of tumors and …
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Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells
Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine fibroids is not well elucidated. Several …
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Characterization of the NADPH oxidase complex in human leiomyoma and normal myometrial smooth muscle cells and its role in PDGF and EGF signaling pathways
Reactive oxygen species have received an increasing amount of attention over the past decade, not only due to their role in oxidative damage, but also because of their participation as second messengers on the relay of many signaling pathways and their role in the development of numeours fibrotic …