Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2413 for “"upstream"”.
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FPGA-based DOCSIS upstream demodulation
… This has intensified demand for the so-called upstream channels, which allow customers to transmit data into the network. The format and protocol of the upstream channels are defined by a set of standards, known as DOCSIS 3.0, which govern the flow of data through the network. Critical to …
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Internal hydraulic jumps with upstream shear
Internal hydraulic jumps in flows with upstream shear are investigated numerically and theoretically. The role of upstream shear has not previously been thoroughly investigated, although it is important in many oceanographic flows such as exchange flows and stratified flow over topography. Several …
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Gsk3 Mediates Signaling Upstream of Akt
… subunits of PI3K, and growth factor receptors upstream of PI3K. Inactivating mutations and decreased expression of the PTEN, a major antagonist of PI3K signaling, also lead to constitutive hyperactivity of Akt. Multiple small molecule inhibitors targeting components of the PI3K/Akt signaling …
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The Novel Upstream Regulator of Fbxw7
<p>SCF<sup>FBXW7</sup> is a tumor suppressor E3 ligase protein that targets numerous oncoproteins such as Cyclin E, c-Myc, c-Jun and MCL1. The deregulation of these proteins often leads to the proliferation of cancer cells. Thus, intracellular stability and functional activity of FBXW7 is critical …
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Internal hydraulic jumps with upstream shear
Internal hydraulic jumps in flows with upstream shear are investigated numerically and theoretically. The role of upstream shear has not previously been thoroughly investigated, although it is important in many oceanographic flows such as exchange flows and stratified flow over topography. Several …
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Aesthetic pollutant loadings in upstream combined sewers.
… that aesthetic pollutants are stored in upstream sewers and private drainage connections during the dry weather period prior to a storm occurring. These pollutants and those within the flow in dry weather are transported out of the sewer at the start of the storm as part of a first foul …
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Investigating upstream regulators of FOXA1 in breast cancer
… inhibition challenging. The identification of upstream regulatory circuitry of FOXA1 would provide potential new avenues for targeting drug-resistant breast cancer. To identify proteins influencing FOXA1 protein stability, we coupled whole-genome CRISPR screening with a reporter system …
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Evaluating upstream supply chain disruptions with partial availability
… the prevalence and severity of disruptions to upstream supply. Disruptions to upstream supply can delay and potentially halt the flow of necessary materials and/or services to purchasing firms, often resulting in severe operational and financial losses. This has created a growing need for …
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Understanding the nutrient sensing branch upstream of mTORC1
mTORC1 is a master regulator of cell growth that responds to diverse environmental inputs and is deregulated in human diseases, such as cancer and epilepsy. One important input to this system is amino acids, such as leucine, which require the Rag GTPases and its regulators, including GATOR1 and …
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High-Fidelity Modeling of Airfoil Interaction with Upstream Turbulence
… on low speed unsteady airfoil responses to upstream disturbances, this work proposes and investigates a method to generate a turbulent momentum source to be convected downstream and interact with an SD7003 airfoil in a high-fidelity numerical simulation. A perturbation velocity field is …
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Looking Upstream: A Sociological Investigation of Mass Public Shootings
<p>In the last 40 years, social scientists have provided important insights into the different characteristics of mass public shootings: their prevalence, types, patterns, and individual risk factors. However, we still lack a fundamental understanding of the processes that shape its incidence and …
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Pressure Disturbance Upstream of the Boundary Layer Data System
… fluid dynamics (CFD) tools in the prediction of upstream surface pressure disturbance and pressure drag of various instrument excrescence shapes for a small aircraft flight test device called the Boundary Layer Data System (BLDS). Insights on pressure disturbance will serve as a guide for the …
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PKA as an Upstream Kinase for LKB1/STRAD/MO25
… complex (LSMK) has been identified as the major upstream kinase for AMP-activated protein kinase (AMPK). PKA phosphorylates LKB1 at the Ser428 residue in humans and Ser431 residue in mice. We investigated PKA as an upstream kinase for LSMK. LKB1 that had been incubated with PKA prior to …
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Upstream history and apparent stress in turbulent boundary layers.
Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Thesis. 1966. Ph.D.
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Effects of stator pressure field on upstream rotor performance
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1996.
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Architecting an Upstream Oil and Gas Enterprise for Innovation
… significant volatility within the energy sector. Upstream oil and gas enterprises, in particular, need to catch up in adapting and adjusting their corporate strategies to embrace cleaner and more sustainable practices in oil and gas production. This highlights the critical need for enterprise …
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Developing an environmental management approach to Libya's upstream petroleum industry.
Concern about environmental impacts of the upstream oil and gas industry in Libya, which is an essential part of the national economy, is increasing following more intensive development of the country's petroleum reserves. The petroleum industry recognises that potential environmental impacts and …
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DOCSIS 3.1 cable modem and upstream channel simulation in MATLAB
… which lead to supporting transmission in the upstream direction (i.e. from subscriber to the head-end). This greatly increased the signal processing to include frequency diplexers. CATV service providers began to expand the bandwidth of their networks in the late 90’s by switching from …
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Upstream Migration Under Shear Flow: Force Generation and Molecular Regulation
… against the direction of blood flow -- upstream migration -- is a mechanically anomalous behavior implicated in hematopoietic stem cell trafficking and immune cell surveillance. Despite the centrality of mechanical force to this process, the forces upstream-migrating cells generate at …
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