Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"undifferentiated pleomorphic sarcoma"”.
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Identification of new therapeutic targets for undifferentiated pleomorphic sarcoma
Undifferentiated pleomorphic sarcoma (UPS) is a rare and highly aggressive soft tissue sarcoma with vast unmet treatment needs, both in curative options and the prolongation of survival. The heterogeneity and limited understanding of the targetable alterations within UPS have proven to be …
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Targeted Inhibition of Pi3K, Mtor, and Igf1R For The Treatment of Undifferentiated Pleomorphic Sarcoma
<p>Undifferentiated pleomorphic sarcoma (UPS) is an aggressive mesenchymal malignancy largely devoid of indicators for its originating tissue. Surgery remains the standard of care, as radiation therapy and systemic chemotherapy have limited efficacy in UPS patients with localized and metastatic …
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Development of novel in vitro platforms to model the lung
… to model lung metastasis of cancers such as undifferentiated pleomorphic sarcoma. Towards this, we first adapted a vasculature-on-a-chip model and showed that heterogeneous cells populations from undifferentiated pleomorphic sarcoma had different extravasation efficiencies in the …