Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"undifferentiated ES cells"”.
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Dynamic histone modifications at the promoters of Hox genes in embryonic stem cells
… associated with changing levels of gene expression, but their role in determining, or possibly predicting, patterns of expression is uncertain. Here, the link between histone modifications and Hoxb gene expression in mouse embryonic stem (ES) cells was explored. Levels of the “active” …
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Cryo-electron microscopy studies of pluripotency factor Nanog
Embryonic stem (ES) cells are derived from the inner cell mass of the blastocyst in the early mammalian embryo. These cells are characterised by the ability to self-renew and to give rise to cell types from all lineages, known as pluripotency. Culture of ES cells in vitro requires addition of …
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Understanding the Dynamics of Embryonic Stem Cell Differentiation
The two defining features of mouse embryonic stem (ES) cells are self-renewal and naive pluripotency, the ability to give rise to all cell lineages in the adult body. In addition to being a unique and interesting cell type, pluripotent ES cells have demonstrated their potential for continued …
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H4K16 acetylation during embryonic stem cell differentiation
… octamer core. The N-terminal tails of the histones protrude through the DNA and can be modified by a variety of enzymes. Acetylation of Histone 4 Lysine 16 (H4K16ac) is an important modification associated with an increase in transcription, and in flies is an important component of the doseage …