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Showing 1 to 1 of 1 for “"undecaprenyl synthesis"”.
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Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections
… active compounds are potent inhibitors against undecaprenyl diphosphate synthase (UPPS), an essential enzyme involved in cell wall biosynthesis pathway. Besides, they bound to an AT-rich DNA dodecamer (CGCGAATTCGCG)2 and were found to increase the melting transition by up to 24 °C using …