Global ETD Search
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Showing 1 to 2 of 2 for “"undecaprenyl diphosphate phosphatase"”.
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ANTIMICROBIAL CHARACTERIZATION AND THERAPEUTIC APPLICATIONS OF NOVEL SYNTHETIC THIAZOLE COMPOUNDS AGAINST MULTIDRUG-RESISTANT STAPHYLOCOCCI AND ENTEROCOCCI
… possible targets: YubA, YubB and YubD. YubB is undecaprenyl diphosphate phosphatase (UPPP) and UPPP as well as undecaprenyl diphosphate synthase (UPPS) were inhibited by 1, as confirmed by traditional enzyme inhibition assays. YubA and YubD are annotated as transporters and may also be targets …
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Mechanistic investigations on polyprenyl transferases and multi-target antibiotic discovery
… Head-to-tail condensations, usually of allylic diphosphates (isoprene units), are catalyzed by head-to-tail prenyl transferases (commonly referred to prenyl diphosphate synthase), and produce regular terpenes which are by far the most common isoprenoid compounds. Head-to-middle prenyl …