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Showing 1 to 2 of 2 for “"ultra-high throughput sequencing"”.

  1. Identification and Characterization of APOBEC1 mRNA Editing Targets: A Transcriptomics Approach

    … intestinal enterocytes. The technique utilizes ultra-high throughput sequencing and subsequent bioinformatic analysis to compare wild-type and congenic apobec1-/- transcriptomes for specific single nucleotide variants indicative of editing. Following technical validation, the screening approach …

    rockefeller Repository record for Identification and Characterization of APOBEC1 mRNA Editing Targets: A Transcriptomics Approach (opens in a new tab)

  2. Bacterial genes and genome dynamics in the environment

    … half of this thesis I present tools to leverage high throughput sequencing for the study of environmental genomes. In the second half of this thesis, I describe modes of environmental adaptation by bacteria via gene content or gene expression evolution. Associating genes' usage and evolution to …

    mit Repository record for Bacterial genes and genome dynamics in the environment (opens in a new tab)