Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 118 for “"ulcerative colitis"”.
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Immunological responses following surgery in ulcerative colitis
… cytokines were studied following surgery for ulcerative colitis (UC). A high prevalence of ANCA was found in UC but not in Crohn’s disease. ANCA positive UC sera were found to recognise a variety of antigens, namely lactoferrin, cathepsin G, enolase and elastase. Confocal microscopy revealed …
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Evaluation of pediatric acute ulcerative colitis management protocol
<p>Pediatric patients with ulcerative colitis (UC) represent a high-risk population with severe disease that requires hospitalization. This study evaluates the impact of implementing an acute UC management protocol on 39 pediatric patients. After analysis, significant trends were shown for admitted …
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Subgrouping Ulcerative Colitis Patients using Administrative Claims Data
… patients in the US have been diagnosed with Ulcerative Colitis, a chronic inflammatory disease affecting the colon. Uncovering patient subgroups could improve treatment guidelines and help physicians choose an appropriate treatment plan for a patient. Here, we outline a Python implementation …
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Effect of Coconut Oil on Ulcerative Colitis in the Mouse Model
<p>Ulcerative colitis (UC) is a chronic disease of the colon or large intestine that causes inflammation and ulceration of the inner lining of the colon and rectum. In patients with ulcerative colitis, the body’s immune system overreacts and the body mistakes food, bacteria or other internal …
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Integrating -Omics For Studying Functional Role Of Ulcerative Colitis Risk Associated Loci.
Background: Ulcerative Colitis is chronic inflammatory condition of unknown etiology. Genome Wide Association Studies have successfully identified large number of UC risk associated loci, majority of which are located in non-protein-coding DNA regions and been showed to be enriched within …
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Investigating the role of IL-4/IL-13 and their receptors in ulcerative colitis
Ulcerative colitis (UC) is a heterogeneous inflammatory bowel disease (IBD) associated with chronic inflammation of the gastrointestinal tract. Characterized by genetic and immunological abnormalities, UC has overly aggressive T-cell responses to commensal bacteria eventually leading to disease …
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Impaired ketogenesis is implicated in intestinal stem cell function and epithelial regeneration in ulcerative colitis
… and regeneration is key to mucosal healing in Ulcerative Colitis (UC). Intestinal stem cells (ISCs) drive this response, proliferating and differentiating from the base of the crypt to regenerate the entire epithelium. ISCs therefore exist in a highly active state and resultantly are vulnerable …
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The effects of treadmill and voluntary wheel training on morbidity and inflammation during ulcerative colitis in mice
Inflammatory bowel diseases (IBD), such as ulcerative colitis (UC), are causes of chronic morbidity that significantly reduce physical functioning and decrease quality of life in afflicted patients. It is well established that pharmacological anti-inflammatory therapies, aimed to decrease colon …
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Clinical Evaluation of Patients with Ulcerative Colitis- Contemporary Approach / Клинична оценка на пациентите с язвен колит-съвременен подход
Дисертационният труд съдържа литературен обзор. Той преставя: етиология, патогенеза, фактори на околната среда, лечение, проследяване на терапевтичния отговор и качество на живот (КЖ) при пациентите с язвен колит (ЯК). Целта е да се извърши оценка на диагностиката, терапия и проследяване на …
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Comparison of Health-related Knowledge and Quality of Life in Outpatients with the Crohn’s Disease and Ulcerative Colitis
… 도구는 질병 관련 지식은 Eaden 등(1999)이 개발한 The Crohn's and Colitis Knowledge(CCKNOW) Score를 연구자가 번역과 역번역한 한국판 도구로 측정하였다. 건강 관련 삶의 질은 Irvine, Zhou와 Thompson(1996)의 Short Inflammatory Bowel Disease Questionnaire (SIBDQ)를 대한장연구학회(2003)가 번안한 한국판 도구로 측정하였다. 본 연구의 주요 결과는 다음과 같다. 1. 본 연구에 참여한 크론병과 궤양성 대장염 대상자의 일반적 …
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Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity
… study was to determine which symptom domains in ulcerative colitis (UC) are important in the evaluation of disease activity. An important symptom is that which 1) occurs during flares, 2) improves during effective therapy, and 3) resolves during remission. Twenty eight symptom domains were …
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Predictors of emergency colectomy in patients admitted to Groote Schuur Hospital with acute severe ulcerative colitis between1st January 2003 and 1st January 2013
INTRODUCTION: Acute Severe Ulcerative Colitis (ASUC) is a life threatening condition which requires urgent and aggressive medical therapy to reduce mortality, morbidity and avoid surgery; the mainstay of treatment is intravenous corticosteroids. To facilitate this process it is essential to …
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Complex Evaluation of the Effectiveness of Biological Therapy in Patients with Active Ulcerative Colitis // Комплексна оценка на ефективността от биологична терапия при болни с активен язвен колит
Inflammatory bowel diseases (IBD), namely ulcerative colitis (UC) and Crohn's disease (CD), are chronic immune-mediated conditions with a high incidence in developed countries and a rapidly increasing incidence in highly industrialized countries. The pathogenesis of UC is complex and still unclear. …
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Intermediates of coenzyme A biosynthesis in colon tissue: Normal vs inflammatory bowel disease
… virtually indistinguishable from chronic ulcerative colitis in humans. The inflammatory lesions in swine were associated with lowered levels of coenzyme A, the biologically active form of pantothenic acid. Colonic mucosal tissue removed from humans with chronic ulcerative colitis or …
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The Impact of Study Methodology on Studying Genetic and Environmental Risk Factors for the Inflammatory Bowel Diseases
… disease (IBD), comprised of Crohn’s disease and ulcerative colitis, results from a complex interaction between genetic and environmental factors. NOD2 and cigarette smoking are two of the most commonly replicated genetic and environmental risk factors, respectively, for Crohn’s disease. Studies …
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Obesity in Patients with Inflammatory Bowel Disease // Затлъстяване при пациенти с хронични възпалителни болести на червата
… markers in the study of patients with ulcerative colitis and Crohn's disease makes them a natural choice to comprehensively evaluate their role. The present study aimed to assess obesity in patients with chronic inflammatory bowel disease (Crohn's disease and ulcerative colitis).
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Geographic Differences in the Risk of Surgery in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
Crohn’s disease (CD) and ulcerative colitis (UC), collectively known as the inflammatory bowel diseases (IBD), are chronic immune mediated conditions. The pathophysiology of these disease is not well understood but genetic predisposition, dietary and microbiome-related factors, and environment …
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Variazione dei markers di attivata coagulazione indotta dalla terapia infusionale con Infliximab in pazienti affetti da malattie infiammatorie croniche intestinali
… mean age: 47.6+17.6 years; 4 Crohn's disease, 4 Ulcerative Colitis,1 Indeterminate Colitis). F1+2 and D-dymer levels were measured in each sample using ELISA methods.The data were statistically analyzed by means of Wilcoxon matched paired test. RESULTS: Median F1+2 levels were markdely reduced 1 …
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