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Showing 1 to 1 of 1 for “"tyrosyl tRNAGUA"”.

  1. A Stress-Induced TRNA Depletion Response Mediates Codon-Based Translational Repression and Growth Suppression

    … stress can rapidly generate tRFs derived from tyrosyl tRNAGUA—resulting in a significant depletion of the precursor tRNA molecule and mature tRNA while also leading to elevated levels of the tRF. Proteomic and ribosomal profiling of tyrosyl tRNAGUA-depleted cells revealed impaired expression of …

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