Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 56 for “"tyrosine hydroxylase"”.
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Tyrosine hydroxylase immunoreactive fibers in the upper layers of the adolescent rat medial prefrontal cortex
… timing of changes. Here, the development of tyrosine hydroxylase-immunoreactive axons, to indicate dopaminergic innervation, in the upper layers of the medial prefrontal cortex was examined in both sexes of Long-Evans rats during five ages from postnatal day 25 to 90. Tyrosine …
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Characterization of Tyrosine Hydroxylase-Positive Neurons Projections from the Paraventricular Nucleus of Hypothalamus to Hindbrain Autonomic Regulatory Centers
… type of excitatory or inhibitory neurons. Tyrosine hydroxylase (TH)-positive neurons in the hypothalamus plays important role in cardiometabolic regulation; however, the anatomical projections of TH neurons in the paraventricular nucleus hypothalamus (PVN) to key parasympathetic and …
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Expression of tyramine β – hydroxylase and tyrosine hydroxylase genes in response to odor valence in the brain of the honey bee, Apis mellifera
… enzymes in OA and DA synthesis, tyramine β – hydroxylase (tbh) and tyrosine hydroxylase (th), respectively, in response to conditioned odor valence. Populations of tbh- and th-expressing neurons in 6 and 4 locations of the bee brain, respectively, were measured. I discovered ventrally …
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Effects of long-term hormone treatment on cognitive behavior and the structure of the medial prefrontal cortex during aging in female rats
… and using immunohistochemistry, stained for tyrosine hydroxylase and synaptophysin. Adjacent sections were Nissl stained to calculate volume and quantify neuron number. The medial prefrontal cortex was examined because it is involved in several cognitive tasks and is known to be sensitive to …
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Alcohol-induced Locomotor Activity in Zebrafish is Mediated by Activation of the Dopaminergic System
… increase in dopamine levels with increased tyrosine hydroxylase activity and protein expression, the rate limiting enzyme in dopamine synthesis. We also found selective inhibition of phosphorylated tyrosine hydroxylase to attenuate the alcohol-induced increase in locomotor activity and …
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Gonadal steroid regulation of luteinizing hormone-releasing hormone and luteinizing hormone release in the male sheep
… not by rapidly reducing LHRH release, and (4) tyrosine hydroxylase-containing neurons of A14 and A15 are activated concomitant with T-induced suppression of LH release. The conclusion from the final study is (5) neuroendocrine mechanisms regulating seasonal changes in LH release are sexually …
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Olfactory ensheathing cell mediated mechanisms of neurite outgrowth and axon regeneration
… OB OEC transplantation, whereas substance-P and tyrosine hydroxylase-positive neurons grew more extensively following OB or LP OEC transplantation, respectively. To further understand the growth of spinal cord neurons in response to OECs, a proteomic analysis of OEC secreted factors was …
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COMT Genotype, Schizophrenia, and Dopamine Transmission
… found for the D1 dopamine receptor, COMT, and tyrosine hydroxylase, the rate-limiting step of dopamine synthesis. The current findings support a model decreased dopamine synthesis and increased catabolism leading to deficient dopamine signal transmission in persons with schizophrenia.
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Reprogramming human somatic cells to pluripotency using RNA
… teratomas in vivo, and differentiated into tyrosine hydroxylase-positive neurons in vitro. Genetic analysis using array comparative genomic hybridization with an 8.9kb median probe spacing demonstrated that RNA reprogramming can yield lines free of copy number variations. The very high …
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Mapping phenotypic traits in swine
… F2 animals genotyped as homozygous 240T, or e/e. Tyrosine hydroxylase was identified as a candidate gene for the region on chromosome 2. Genomic sequence for tyrosine hydroxylase was generated and the population was genotyped for an A159T mutation. All solid white individuals except two genotyped …
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Vulnerability to cognitive, neurotoxic and neuroinflammatory effects of toxins that induce Parkinson's disease after administration of amphetamine-related drugs in mice
… Degeneration of dopaminergic neurons by tyrosine hydroxylase (TH) immunohistochemistry in SNc and striatum was also evaluated. Neurochemical evaluations were paired with assessment of cognitive performance by means of the novel object recognition (NOR) and spontaneous alternation in a …
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Study on the Neuroprotective Effects of Ethyl pyurvate in MPTP-induced Mouse PD Models
… DA neurons and glial activation as visualized by tyrosine hydroxylase, macrophage antigen complex-1, and/or glial fibrillary acidic protein immunoreactivity. Western blotting and immunohistochemistry showed activation of microglial NADPH oxidase and astroglial myeloperoxidase (MPO), and subsequent …
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CBD & Ethanol Disrupt Early Embryonic Development
… exposure. Furthermore, a large variance in tyrosine hydroxylase expression in diencephalic dopaminergic nuclei was observed with CBD exposure. These data suggest that early impairments potentially caused by chronic CBD exposure during embryonic development and changes in TH expression during …
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Contributions of Reward Identity and Time Prediction Errors to Pavlovian Learning
… (p-rPS6) and the dopamine (DA) precursor tyrosine hydroxylase (TH). Reward identity PEs did not result in activation of neurons in the orbitofrontal cortex (OFC), basolateral amygdala (BLA), or any component of the striatum. In contrast, reward identity PEs did result in the recruitment of …
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Pathological changes in mesostriatal neurons in a PKC-gamma mutant rat
… aminergic cell bodies to synthesis transmitters; tyrosine hydroxylase (TH) in the dopaminergic neurons and serotonin (5-HT) in the serotonergic neurons (b) those which have been found to occur in human neurodegenerative conditions such as Parkinson’s disease: ubiquitin, parkin and α-synuclein …
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H5N1 Influenza Virus Induces a Parkinsonian Pathology
… 1) substantia nigra pars compacta (SNpc) tyrosine hydroxylase positive dopaminergic neuron number and striatal dopamine and its metabolites contents through 90 days post infection (dpi), 2) examined the inflammatory effect of infection by quantitatively measuring the total number of …
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The Neuroinflammatory Effects of Chronic Unpredictable Stress on Zebrafish, Danio rerio
… statistic, and the single pairwise difference in tyrosine hydroxylase (TH) expression, suggesting that stress still may induce anxiety behaviors and affect the neurocircuits that modulate stress. These outliers prompt additional trials with larger sample sizes.<strong></strong></p>
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The neurobiology of central dopamine and progesterone in the reproductive cycle of the ring dove (Streptopelia risoria)
… breeding cycle, and provide the first mapping of tyrosine hydroxylase immunoreactive (Til-ir) structures in the ring dove brain. Quantitative analysis revealed increased TFJ-ir cells, in male and female brooding doves, in the nuclei periventricularis magnocellularis, dorsomedialis anterior …
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