Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 48 for “"type 1 diabetes mellitus"”.
-
Immunomodulation of dendritic cells in autoimmune type 1 diabetes mellitus.
Immunomodulation of dendritic cells in autoimmune type 1 diabetes mellitus.
-
Auditory-vestibular function in adults with type 1 diabetes mellitus
Diabetes mellitus (DM) is a universal health problem. According to the International Diabetes Federation (IDF), 425 million people world-wide are affected by DM. With such high incidence of DM, health professionals aim to avoid possible secondary disorders which impact health related quality of …
-
Improving Pediatric Type-1 Diabetes Mellitus Management in Rural Utah: A Case Study
… in a rural area is associated with poorer diabetes care The rural adolescent patient described in this case study has a well-documented history of poor T1DM control. Her pediatric endocrinologist is located over 2 hours away from her home. Reported blood glucose levels average above 200 …
-
An Investigation for Genetic Susceptibility to Type 1 Diabetes Mellitus and its Microvascular Complications
Long-term exposure to diabetes mellitus is associated with metabolic abnormalities such as chronic hyperglycemia and redox imbalance. Uncontrolled hyperglycaemia and genetic factors are implicated in the pathogenesis of diabetic microvascular diseases. Genetic mutation through the genes coding for …
-
A qualitative study on the experiences of mothers of adolescents with Type 1 diabetes mellitus
Type 1 diabetes is an important chronic endocrine illness of adolescence. It presents a range of unique and difficult to manage problems by virtue of the developmental challenges that face adolescents. Medical services are often ill equipped to deal with this patient group while the complicated …
-
Increased Lipid Metabolism in Response to Repetitive Aerobic Exercise During Proestrus in Type 1 Diabetes Mellitus Rats
… to repetitive bouts of aerobic exercise, type I diabetes mellitus (T1DM) female rats demonstrate greater post-exercise blood glucose (BG) recovery during proestrus than T1DM males. Fuel selection differences may explain sex-related differences in the blunted counterregulatory responses to …
-
A Comparison of ADRR Scores in Very Young, School-age, and Adolescent Children with Type 1 Diabetes Mellitus
Glycemic variability (GV) in children is remarkably dissimilar to GV in adults, and furthermore is unique to age-specific pediatric groups. The Average Daily Risk Range score has been shown to be a good indicator of GV in adults and some children; however, there are no data examining youths' ADRR …
-
Continuous Subcutaneous Insulin Infusion in Comparison to Subcutaneous Insulin Injections in the Preschooler with Type 1 Diabetes Mellitus
<p>Type 1 Diabetes Mellitus is a form of diabetes that results from autoimmune destruction of insulin-producing beta cells of the pancreas subsequently causing a lack of insulin and leading to increased blood and urine glucose (Cihakova, 2001). Type 1 diabetes has increased at an alarming rate in …
-
Characterizing neurodegeneration, neuroinflammation and immunological status through multimodal strategies in type 1 diabetes mellitus and relapsing-remitting multiple sclerosis
Type 1 diabetes mellitus (T1DM) and Multiple sclerosis (MS) are chronic organ-specific diseases caused by immune system dysfunction. The study of T1DM and MS has gained increasing attention because of their high prevalence, progressive nature, impact on patients' daily lives, the lifelong …
-
A Qualitative Exploration of Self-Care Behaviors for Disease and Symptom Management Among College Students with Type 1 Diabetes Mellitus
… of college students have been diagnosed with Type 1 Diabetes Mellitus (T1DM), the effects of inadequate management can lead to hospitalizations, additional development of chronic health conditions, and early mortality. Therefore, T1DM self-care behaviors (e.g., administering insulin, …
-
Type 1 diabetes mellitus and the brain: influence of clinical complications and genetic factors on brain structure and cognitive function
Type 1 diabetes mellitus is characterised by absolute insulin deficiency, chronic hyperglycaemia and intermittent hypoglycaemia consequent upon treatment with insulin. Severe hypoglycaemia, defined as hypoglycaemia sufficient to necessitate third party intervention for recovery, commonly …
-
Fear of needles among children and adolescents with type 1 diabetes mellitus : relationship with metabolic control (HbA1c) and quality of life
… of needles among children and adolescents with type 1 diabetes mellitus and its effects on the quality of metabolic control measured with haemoglobin A1c (HbA1c) and quality of life. Method: 33 patients aged 9-16 years old with type 1 diabetes mellitus were enrolled in the study as well as their …
-
Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life
… various psychosocial factors (perceived stress, diabetes-specific parental involvement, self-efficacy for diabetes management, and perceived peer support) on adolescents’ self-reported health-related quality of life (HRQoL) and assess the association between these factors and their self-reported …
-
Feasibility and acceptability of a mother-daughter intervention to address disordered eating behavior among adolescent girls living with type 1 diabetes mellitus
… psychological illnesses. Adolescent females with Type-1diabetes (T1DM) are at higher risk for DEB and have a two-fold higher incidence of disordered eating behavior (DEB) than their non-diabetic counterparts. Individuals with T1DM have the unique ability to omit insulin as a weight reduction …
-
The impacts of a health education programme on primary school teachers' knowledge and attitudes towards type 1 diabetes mellitus in children in Saudi Arabia
… prevention, treatment and management of Type 1 Diabetes Mellitus (T1DM). Teachers need to be knowledgeable about diabetic emergences.AimThe aim of this study was to assess the impact of a health education programme on primary school teachers' knowledge and attitudes towards T1DM in …
-
A 4-month randomized controlled clinical trial of adjuvant exenatide or pramlintide versus insulin alone in pediatric type 1 diabetes mellitus: Effect on glycemic control
… (1,5-AG), or GlycoMark, in pediatric Type 1 Diabetes Mellitus (T1DM). We present here the preliminary results (n=24) of a Phase III randomized clinical trial designed to compare the glycemic effects of using adjuvant Pramlintide or Exenatide versus insulin alone in pediatric T1DM. …
-
The impact of closed-loop insulin delivery on glucose control in children and young people with type 1 diabetes mellitus: Longer-term benefits across the paediatric age-spectrum
Type 1 diabetes is one of the most common chronic conditions of childhood and is characterised by a deficiency of insulin caused by immune-mediated destruction of pancreatic beta cells in genetically predisposed individuals. Despite increasing technology use to manage type 1 diabetes, most children …
-
Microrna 21 targets B Cell Lymphoma 2 (Bcl2) Mrna to increase beta cell apoptosis and exosomal Microrna 21 could serve as a biomarker of developing Type 1 Diabetes Mellitus
The role of beta cell miR-21 in Type 1 Diabetes (T1D) pathophysiology has been controversial. Here, we sought to define the context of beta cell miR-21 upregulation in T1D and the phenotype of beta cell miR-21 overexpression through target identification. Furthermore, we sought to identify whether …
-
Differentiation of mouse embryonic stem cells into insulin-producing cells: optimization to enhance the overall differentiation efficiency
… potential to differentiate into multiple cell types including insulin-producing cells (IPCs), which is becoming one of the promising cell sources for treating type 1 diabetes mellitus. However, in order to achieve functional stem cell-derived cells, it is important to generate more mature IPCs …
Page 1 of 3