Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"tympanic membrane"”.
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Clinical Characteristics and Patterns of Chronic Tympanic Membrane Perforations
고막 천공은 이비인후과 외래에서 비교적 자주 접할 수 있는 질환으로, 일반적으로 고막 천공의 크기가 큰 경우, 변연 천공인 경우, 또는 지속적인 감염의 경우에 만성화되는 경향이 있다. 고막의 재생 능력은 우수한 것으로 알려져 있지만 아직 그 기전이 명확히 밝혀져 있지는 않다. 따라서 본 연구는 만성 고막 천공의 유형과 특징을 분석하고 재생과정에서 보이는 경향에 대해 알아보고자 하였으며, 이러한 임상적 특징을 다른 동물 실험등과 비교하여 고막 재생 기전을 확립하고 새로운 재생 기술을 개발하고자 하였다. 본 이비인후과에서 …
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Quantifying tympanic membrane dynamics in otitis media using low coherence interferometry
Examining middle ear dynamics and mobility of the tympanic membrane (TM) is essential when diagnosing otitis media (OM), or a middle ear infection. OM is a widespread infectious disease in childhood, characterized by the accumulation of middle ear fluid, known as middle ear effusion (MEE). Loss of …
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Effects of tympanic-membrane perforations on middle-ear sound transmission : measurements, mechanisms, and models
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1998.
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Middle-Ear Imaging and Estimation of The Linear Elastic Properties of The Human Tympanic Membrane
… the linear elastic properties of the human tympanic membrane (TM). In the imaging study, six human temporal bones were used, which were obtained in right-left pairs, from three cadaveric heads. All bones were fixed using formaldehyde. Only one bone from each pair was stained using IKI …
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The effect of smooth muscle antagonists on the sound-induced motion of the tympanic membrane
The pars tensa of the tympanic membrane is composed of three layers: an epidermal layer, a fibrous layer, and a mucosal layer. Recent studies (Kuijpers et al, 1999; Henson and Henson, 2000; Henson et al, 2005) suggest that the fibrous layer in several mammalian species contains contractile fibers, …
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Development of New Regeneration Methods in Animal Models with Chronic Tympanic membrane Perforations Using Tissue Engineering Techniques
Tympanic Membrane (TM) perforation, in particular chronic otitis media, is one of the most frequent clinical problems in the otolaryngology field, which sometimes presents conductive healing loss. This study consists of three purposes and experiments; 1) we developed new animal models for chronic …
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Migration of human tympanic epithelium in health and disease
… function in the maintenance of this delicate membrane by removing dead squamous epithelium to the external meatus for dispersal. The abnormal presence of the same epithelium in the middle ear space produces a proliferating, expanding mass which cannot escape from its enclosed environment. This …
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Clinical translation of optical coherence tomography for the diagnosis of otitis media: validation and tracking of biofilms on the tympanic membrane and development of a novel automated classification and diagnostic platform
… affixed on the internal mucosal surface of the tympanic membrane (TM) using OCT. These structures have not been identified or analyzed by any characterization technique, or observed for the response to standard of care treatment of OM. Furthermore, OCT experts have been primarily responsible for …
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A multispectral imaging method and device to detect and quantify the presence of fluid in the middle ear to facilitate the diagnosis and triage of ear infections
… or otitis media that cause inflammation of tympanic membrane and fluid buildup in the middle ear cavity accounts for 2-3 million hospital visits every year [34]. As per an epidemiological study conducted from 2006 - 2016 on 685 children, between the ages of 1-3 years, roughly 60% had at …
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Using otoacoustic emissions to measure the transmission matrix of the middle-ear
… assumes that the input-output response at the tympanic membrane and stapes footplate is linear, one dimensional and time invariant. The technique allows for estimating the acoustic pressure and volume velocity at the tympanic membrane and the volume velocity of the stapes footplate, in both the …
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A Provacative Test to Determine Brain Compliance in the Management of Patients with Hydrocephalus
… the digital and supraorbital arteries as well as tympanic membrane displacement. This requires the use of two photo-plethysmographic sensors and a TMD sensor. A common tilt table apparatus is used to methodically and artificially increase intracranial pressure to stress the cranial system during …
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Lorentz-force actuated needle-free injection for intratympanic pharmaceutical delivery
… to the inner ear via injection through the tympanic membrane is a method of local drug delivery that provides a non-invasive, outpatient procedure to treat many of the disorders and diseases that plague the inner ear. The real-time controlled linear Lorentz-force actuated jet injector …
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Auditory system comparisons between sand cats and other felid species : acoustic input admittance of ears and auditory brainstem responses
… associated with increased power absorbed at the tympanic membrane.
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Non-invasive assessment of bacterial biofilm in the middle ear using low-coherence interferometry/optical coherence tomography and acoustic measurements
… infection caused by bacterial growth between the tympanic membrane (TM) and the inner ear. Children with chronic OM, including OM with effusion and recurrent OM, often have conductive hearing loss and communication difficulties, and need surgical treatment. Recent clinical studies have shown …
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Non-invasive optical quantification of otitis media and middle ear effusions
… A clinical study was organized to observe the tympanic membrane of patients with normal, acute, and chronic infections in an attempt to identify differentiating characteristics of each infection state. Following this work, algorithms were developed to identify and quantify middle ear effusions. …
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Non-invasive assessment of biofilm growth in the middle ear using a portable low-coherence interferometry system
… accompanied by a bacterial biofilm behind the tympanic membrane (eardrum). Biofilms are typically very thin, making them difficult to be recognized using a regular otoscope. However, lowcoherence interferometry (LCI) is capable of detecting and quantifying this microstructure. The goal of this …
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The hearing abilities and middle ear functioning of the recreational scuba diver
… a more permanent effect on the elasticity of the tympanic membrane. Finally this study aims to increase the awareness of possible risks concerning the auditory system relating to scuba diving and in so doing, attribute to the prevention, diagnosing and intervention of diving related ear injuries.
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Optical coherence vibrography : a quantitative tool for probing auditory and ocular biomechanics
… in the middle-ear ossicular chain and in the tympanic membrane are fundamental to hearing. Using the chinchilla ear as a model, we investigate the vibrational amplitude and phase as a function of sound frequency. Our 3-dimensional measurements reveal with unprecedented detail the modes of …
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Chemical penetration enhancers and in situ-forming reservoirs for trans-tympanic drug delivery : progress toward improved treatment of Otitis media
… release reservoirs for noninvasive trans-tympanic treatment of OM. A hydrogel that includes potentially synergistic chemical penetration enhancer (CPE) combinations and an antimicrobial sufficiently increases antimicrobial flux such that therapeutic levels can traverse the tympanic …
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The BOLD MRI response of the brain to alterations in arterial blood pressure
… Arterial and venous blood pressure and tympanic membrane displacement (TMD) measurements were also made during these challenges. Blood pressure data was used to drive two linked models. The first model represented cerebral vascular physiology (Ursino) and this fed into a second model …
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