Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"two-photon calcium imaging"”.
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Two-photon calcium imaging sequence Analysis Pipeline : a method for analyzing neuronal network activity
Investigating the development of neuronal networks can help us to identify new therapies and treatments for conditions that affect the brain, such as autism and Alzheimer's disease. Two-photon calcium imaging has been a powerful tool for the investigation of the development of neuronal networks. …
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Using machine learning for analysis of neuronal network activity
… neuronal activity in developing neuronal networks can improve our understanding of neuronal dysfunctions underlying conditions such as Rett syndrome. Two-photon calcium imaging is used to capture neuronal network activity over time. This method produces large sets of images that are …
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Development and plasticity of the functional laminar mesoscale organization of the primary auditory cortex
… The work in this dissertation uses in vivo two-photon calcium imaging in mice to investigate how the population dynamics of auditory neurons within thalamorecipient layer 4 and supragranular layers 2/3 change over development – from before ear opening, through the critical period for …
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Acetylcholine dynamics in the retrosplenial cortex during spatial uncertainty
… for spatial navigation and the default mode network, integrating egocentric and allocentric inputs, contextual information, and multiple spatial hypotheses. This positions the RSC as a key region for investigating how the brain represents uncertainty. Computational theories propose that …
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Visual perception of social groups in zebrafish
… zebrafish by combining behavioural assays with two-photon calcium imaging. In particular, I investigate how specific group visual features - such as number of elements, speed and overall amount of motion - might influence shoaling behaviour and be integrated within a dorsal thalamic circuit for …
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Understanding experience-dependent plasticity of cellular and network activity in the mouse primary visual cortex
… the lack of studies regarding the cellular and network activity changes coincident with the induction of SRP, we have used calcium indicator expressing mice to visualize cellular activity across days of SRP training. Using two-photon calcium imaging, we found that there is indeed no significant …
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Signal transformation at the input and output of the Drosophila visual system
… the filtering property of visual neurons at two levels, biophysical and circuit levels. The first study looks at signal transformation at the biophysical level, at the input of the visual system, in photoreceptors. Voltage-gated potassium channels counteract the depolarization caused by …
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Nonlinear Representation of Auditory Stimuli Across the Auditory Cortex
… complex auditory sounds, we performed 2-photon calcium imaging of neural activity of the entire auditory cortex in awake mice, while playing sounds composed of single or multiple frequencies. While we observed simple tuning in response to single frequency stimuli, the calcium responses to …
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Neural Mechanisms of Homeostatic Need and Reward
… animal species including human. This thus raises two key questions in neurobiology of need and homeostasis: 1. How do need-sensing neurons maintain physiological homeostasis? How does dysregulation of need-sensing neurons cause diseases? The present thesis aims to study these two questions, …