Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"two-component regulatory system"”.
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Characterization of Hpk2-Rrp2, two-component regulatory system in Treponema denticola
… (response regulator) constitute a functional two component regulatory system that regulates, at least in part, responses to the changing environmental conditions associated with the development of periodontal disease. The results presented demonstrate that tde1970 and tde1969 are conserved, …
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Characterization of the two-component regulatory system ArlRS in Staphylococcus aureus
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-05-01
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Regulation of pilus production by the PilR/PilS two-component and Agr-like quorum sensing systems in Clostridium perfringens
… the VR-10B allele of the VR-10 locus. There are two genes downstream of the pilin genes encoding a two-component regulatory system (PilR/PilS). However, the regulatory function of PilR/PilS remains to be determined. The current study has investigated the function of PilR/PilS in the regulation of …
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Identification of the role of the sal locus in streptococcus pyogenes virulence during host-pathogen interactions
… The focus of this project was the SalKR two-component regulatory system, which facilitates bacterial adaptation by responding to environmental signals during host pathogen-interactions. The first goal of this project was to determine a role in virulence for the SalKR regulatory system. …
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Structural Studies of the Receiver Domain of LytR from Staphylococcus Aureus and Interaction Studies of TraW and TrbC from the F Plasmid of Escherichia Coli
… concern to human health. Bacteria use various systems in combination or alone in response to environmental stressors and stimuli to adapt to changing conditions. Such systems include the two-component regulatory system (TCS) and the type IV secretion system (T4SS). Microbes use TCSs to regulate …
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Characterization of the Activation of the FlgSR Two-Component System in Campylobacter Jejuni
… the flagellar export apparatus, sigma54, and a two-component regulatory system comprised of the FlgS sensor kinase and the FlgR response regulator to activate transcription of the middle and late sigma54-dependent flagellar genes. The FlgR response regulator is an NtrC-like protein that can be …
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Coordinate Regulation of Salmonella Virulence Gene Expression During Infection
… from mild gastroenteritis to life threatening systemic infections. An important step during a S. typhimurium infection is the invasion of non-phagocytic epithelial cells. Invasion is mediated by a Type Three Secretion System (TTSS), which is encoded on Salmonella Pathogenicity Island 1 (SPI1). …
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Regulation of the Salmonella Pathogenicity Island 1 Type Three Secretion System
… is mediated by a Type Three Secretion System (T3SS) encoded on Salmonella pathogenicity island 1 (SPI1). The SPI1 TTSS injects effector proteins into the cytosol of host cells where they promote actin rearrangement and engulfment of the bacteria. HilC, HilD, and RtsA activate expression …
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Signaling Specificity in a Campylobacter jejuni Two-Component System to Mediate Proper Flagellar Gene Transcription
… σ factors, whose activities are controlled by a regulatory cascade. Previous genetic screens discovered the flagellar type III secretion system (T3SS), the FlgSR two-component regulatory system (TCS), and the FlhF GTPase as requirements to positively regulate expression of σ54-dependent genes …
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Potential of bacteriocin producing bacteria to control VRE infection
… resulted in a 9 log decrease in cfu/mL after a two hour period but a number of cells did survive. The phenotype of these cells was assessed, and they exhibited a high level of resistance to Avicin (MIC 45-90μg/mL). More importantly these colonies exhibited decreased resistance to vancomycin …
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Regulation of virulence in Salmonella enterica
… genes involved in both invasion and the systemic stages of infection. Salmonella uses the Salmonella Pathogenicity Island I (SPI1) Type Three Secretion System (T3SS) to invade intestinal epithelia in the distal ileum of the host small intestine. HilA, a master regulator of the system, …