Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"two component signal transduction systems"”.
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Specificity and evolution of bacterial two-component signal transduction systems
… capacity to sense and process a diverse range of signals. Duplication and divergence of a relatively small number of gene families has provided the raw material enabling cells to quickly increase their signaling capacity. After duplication, however, all pathway components are identical in sequence …
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Role of the Nla6S and Nla28S histidine kinases in fruiting body development of <i>Myxococcus xanthus</i>
… structures known as fruiting bodies. Two component signal transduction systems (TCS) are widely used by bacteria to detect and respond to environmental cues by regulating large-scale changes in gene expression. They contain a histidine kinase sensor that detects environmental cues and …
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Regulation of amylovoran biosynthesis in Erwinia amylovora
… diseases for the apple and pear industry. Two pathogenicity factors strictly required for E. amylovora to cause disease are the exopolysaccharide amylovoran and the type III secretion system. In bacteria, the two-component signal transduction (TCST) system is the major paradigm to sense …
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Understanding the Genetics and Evolution of Antimicrobial Resistance in Escherichia Coli
… coli. Finally, to gain understanding of the network of genes contributing to intrinsic and phenotypic resistance, I have studiedE. coli's two-component signal transduction systems (TCS). TCSs are involved in bacterial responses to many stresses, including antibiotics. I examined interactions …
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Characterization of major virulence regulators of Erwinia amylovora
… and type III secretion system (T3SS) are two major virulence factors in E. amylovora. However, how these virulence factors are regulated is not completely understood. In bacteria, gene expression is mainly regulated at the transcription initiation level and its core RNA polymerase (RNAP) …
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Regulation of clostridium acetobutylicum glutamine synthetase glnA gene
… the family of the response regulators involving two component signal transduction systems, suggesting that the protein encoded by this ORF may play a role in the mechanism of regulation of the C. acetobutylicum glnA gene in response to nitrogen.
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Overexpression, purification and ligand interaction studies of intact membrane sensory kinases from enterococci: towards agonist and antagonist screening
Two component signal transduction systems are of great importance in the regulation of expression of many virulence traits in bacteria and are a vital component of the way bacteria sense and respond to their environment. The sensor kinase component is generally membrane bound and is involved in …