Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"tumour-associated macrophage"”.
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Oxime Click-crosslinked Cryogels to Quantify and Target Tumour-associated Macrophage Invasion in Hodgkin Lymphoma
… cancer cells account for less than 5% of the tumour microenvironment, yet drug screening and treatment strategies typically focus on targeting malignant cells. Tumour-associated macrophages (TAMs) are associated with poor prognosis and resistance to therapy; however, there remains an unmet …
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Molecular dissection of macrophage-tumour cell interactions to identify novel treatment strategies for pancreatic cancer
… is one of the most aggressive forms of adult tumours with a median survival time of twelve months. PDAC is highly resistant to conventional therapy which includes surgical resection of the tumour, radiation treatment and chemotherapy. PDAC cells are highly motile and invasive resulting in …
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Crosstalk between colorectal cancer cells and tumour-associated macrophages
… development of CRC is highly influenced by the tumour microenvironment. Tumour cells are able to recruit macrophages and change their behaviour. These tumour-associated macrophages (TAMs) were of the M2 phenotype (CD206+). In CRC patient tissues and xenografts from mouse model, presence of …
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Programmed cell death-ligand 1 (PD-L1) expression in HIV-associated diffuse large B-cell lymphoma – role and regulation
… settings. Emerging data indicate that HIV-associated DLBCL, although highly heterogeneous, has distinct clinical, morphological and molecular features from non-HIV-related DLBCL. The complex biology that underpins HIV-associated DLBCL remains largely undefined, necessitating clinical and …