Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"tumour clonality"”.
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Tumour evolution and novel biomarkers in breast cancer
… related recurrences and independent primary tumours due to potentially differing prognoses and treatment regimes. Currently, there is no consensus on how to define clonal relatedness between multiple tumours in the same patient. In Paper II, we identified the Similarity Index (SI) as the most …
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Latent feature models and non-invasive clonal reconstruction
Intratumoural heterogeneity complicates the molecular interpretation of biopsies, as multiple distinct tumour genomes are sampled and analysed at once. Ignoring the presence of these populations can lead to erroneous conclusions, and so a correct analysis must account for the clonal structure of …