Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"tumoroids"”.
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Protein L Functionalized Microparticles For Early Detection of Surface Markers In Heterogeneous Colorectal Lesions
… surface targets. Using CRC cell heterogeneous tumoroids (HET-tumoroids) and orthotopic animal models expressing different surface antigens, we demonstrated that 1) Antibody-Protein L functionalized MPs identify Mucin 1 (MUC1) and epithelial cell adhesion molecule EpCAM positive tumoroids …
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Establishment of new human and mouse liver cancer models and their use to uncover the role of RNF43 and ZNRF3 in liver homeostasis and repair
… Interestingly, the tumour-derived organoids (tumoroids) recapitulate the original tumour histology and genetic alterations and are also able to generate tumours in an in vivo xenograft mouse model after long-term expansion. Furthermore, we have shown that tumoroids can also be successfully …
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Tissue-Specific Matrix Control of Cell Cohesion and Migration Signaling Complexes
… to control the cohesion-dyscohesion axis of PCa tumoroids, indicative of its role in controlling PCa metastasis. Taken together, the discoveries from this work can be leveraged to create new treatment options that control cell behavior for those patients with damaged glands experiencing …
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Utilising Single-Cell Technology to Investigate Gene Regulation
… complex tissues, ranging from organoids to tumoroids, researchers can map individual gene expression profiles that correspond to distinct cellular identities and functions. This method has led to the discovery and classification of previously unrecognised cell types and dynamic cellular …