Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"tumor shrinkage"”.
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Comparison of Tumor Shrinkage and Cumulative Dose Distribution For Lung Cancers
… no dose to the normal tissue distal to the tumor. Previously, numerous studies have shown unique advantages of proton therapy over intensity-modulated radiation therapy (IMRT) in conforming dose to the tumor and sparing dose to the surrounding normal tissues and the critical structures in …
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Radiomics of Nsclc: Quantitative Ct Image Feature Characterization and Tumor Shrinkage Prediction
… care computed tomography (CT) images to improve tumor diagnosis, staging, and response assessment.</p> <p>The first objective of this work was to show that CT image features extracted from pre-treatment NSCLC tumors could be used to predict tumor shrinkage in response to therapy. This is …
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Design of an intraperitoneal drug-release device for advanced ovarian cancer therapy
… cancer each year. The standard of care is tumor-debulking surgery followed by adjuvant chemotherapy. Combination intraperitoneal (IP) and intravenous (IV) chemotherapy has been shown to lengthen survival over IV therapy alone. Large-volume infusions, drug-associated toxicity, and …
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Study of Natural Killer Cells and Their Therapeutic Role in Pediatric Cancer
… the natural defense against viral infections and tumor immune surveillance. Through complex interactions between NK cell receptors and target cell ligands, transformed or unhealthy cells are identified and rapidly eliminated. NK cells have been used for therapeutic purposes in pediatric oncology, …
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Course of clinical response during primary systemic therapy with a dose-dense 4 cycles regime of adriamycin and docetaxel in patients with operable cancer of the breast
… chemosensitivity test. One possibility to assess tumor response is the consideration and analysis of clinical parameters such as palpation of the tumor size. <br>Up to now, little is known about typical courses of tumor shrinkage or growth under PST. <br>The results of this dissertation support …
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Use of Echogenic Immunoliposomes For Delivery of Both Drug and Stem Cells For Inhibition of Atheroma Progression
… for VEGF-A which was developed as an anti-tumor agent. Often, anti-VEGF agents result in regression of existing microvessels, inhibiting tumor growth and possibly causing tumor shrinkage with time. During atheroma progression neovasculation in the arterial adventitia is mediated by VEGF. …
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Engineering translational multi-therapeutic targeted delivery vehicles for disease management
… for synergistic cancer therapy, improving tumor cell killing in vitro and significant tumor shrinkage in in vivo murine triple-negative breast cancer and non-small cell lung cancer models. In Chapters 6 and 7, we applied this approach for targeted combination therapeutic delivery for …
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Robust Treatment Planning and Robustness Evaluation for Proton Therapy of Head and Neck Cancer
… positioning, as well as treatment-induced tumor shrinkage and patient weight variations. For IMPT plans using a PTV margin expansion, these anatomical variations might disturb the calculated nominal plan, with a decrease to the dose delivered to the target volume and/or increased dose to …