Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"tumor necrosis factor-alpha (TNF-α)"”.
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Measuring the Changes in Tumor Necrosis Factor-Alpha (TNF-α) from Secretory Populations of U937 Monocytic Cells during Differentiation.
<p>Tumor necrosis factor-alpha (TNF-α) is a cytokine produced primarily by macrophages during acute inflammation. In this study we examined the differential effect of retinoic acid (RA) and phorbol 12-myristate 13-acetate (PMA) on the induction of TNF-α secretion from U937 monocytic cell …
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Association Between Fluoride Exposure and Immune System Biomarkers in Pregnancy
… biomarkers included interleukin (IL)-6, IL-8, tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1 (MCP-1), and C- reactive protein (CRP) from plasma samples collected during the third trimester of pregnancy. Results: We observed a departure from linearity in the association …
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The Effect of Adenosine on the Production of Inflammatory Mediators By Macrophages in Response to Candida Albicans
… inflammatory mediators, including the cytokines tumor necrosis factor alpha (TNF-α) and interleukin 1 (IL-1). Adenosine is an important physiological molecule that can modulate the function of macrophages by altering the amounts of cytokine produced. The effect of adenosine on the production of …
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Distributed Feedback Laser Biosensor in Microplate Format
… layers. An assay for detection of the cytokine tumor necrosis factor-alpha (TNF-α) was used to demonstrate the operation of the sensor in the context of label-free detection of a disease biomarker. The demonstrated capability represents an important step towards roll-to-roll manufacturability …
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CYTOKINE CONTROL OF GLIOMA ADHESION AND MIGRATION
… the most lethal primary central nervous system tumor, with median survival after diagnosis of less than 12 months because dissemination into the brain parenchyma limits the long-term effectiveness of surgical resection, and because GBM cells are resistant to radiation and chemotherapy. This sad …
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Identifying Depression Utilizing Tumor Necrosis Factor–[alpha] and Endothelial Function in Spinal Cord Injury
… symptomology, biomarker derangement of tumor necrosis factor-alpha (TNF-α), and endothelial function in people with SCI. SCI participants showed higher levels of depression, TNF-α and shorter time to reach maximum level of nitric oxide (NO)-dependent vasodilation. Although these …
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Direct Regulation of Apoptosis By Linear Ubiqutin Chain Assembly Complex (Lubac) and Feedback Regulation of Lubac Function By Caspases
<p>Tumor Necrosis Factor-alpha (TNF-α) is a cytokine that plays a role in various cellular processes such as proliferation, differentiation (mainly through NF-κB signaling) and death (via apoptosis signaling). Recently, linear ubiquitination by LUBAC (linear ubiquitin chain assembly complex) was …
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Avaliação de genes auto inflamatórios em crianças com Síndrome Inflamatória Multissistêmica Pediátrica (SIM-P) associada à infecção pelo SARS-CoV-2
… a protease implicated in the processing of tumor necrosis factor-alpha (TNF-α) and plays a crucial role in SARS-CoV-2 infection by cleaving Angiotensin-Converting Enzyme 2 (ACE2), the primary human receptor for SARS-CoV-2. Conclusion: Our data suggest that rare deleterious variants in genes …
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Analysis of Dietary Intake, Body Composition and Biomarkers in Adults with Type 2 Diabetes Mellitus, Prediabetes and Without Diabetes
… (high sensitivity-C-reactive protein (HS-CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6)) between adults with type 2 diabetes mellitus (T2DM) and prediabetes (PDM) to adults without diabetes. A total of 22 participants (PDM/T2DM n=12, controls n=10) in the San Luis Obispo, CA …
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The Level of Antiacetylcholine Receptor Antibodies in the Patients with Myasthenia Gravis
… by immunotherapy. The authors studied which factors correlated with the level of antiacetylcholine antibodies and which cytokines were affected by immunotherapy. Thirty three patients with MG were included in this study. Diagnosis of MG depended on the typical clinical manifestation and one …
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The influence of equine bone marrow derived stem cells on the response of cultured peripheral blood mononuclear cells to endotoxin
… After stimulation with endotoxin, secretion of tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10), and interferon gamma (IFN-γ) were determined by ELISA. The immunogenic properties of MSCs were assessed with a one-way mixed lymphocyte reaction. In addition, the …
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Autoimmune Responses to Atherosclerotic Lipids: A Study In Murine Models of Atherosclerosis and Obesity
… in spleens of db/db mice with hyperlipidemia. Tumor necrosis factor-alpha (TNF-α) was increased in db/db spleen, while TNF-α receptor expression augmented in the db/db murine heart, in comparison with those in normal mice. The nuclear factor-κ B (NF-κB) expression was enhanced in the db/db …
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The Study of Serial Histochemical Changes in Laser-related Post-inflammatory Hyperpigmentation
… proteins and paracrine melanogenic factors are regulated by laser surgery, time-sequential immunohistochemical studies were performed with Q-switched alexandrite laser (QSL)-irradiated skin of four healthy subjects. Skin biopsies were performed at baseline first and then immediately, …
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Tail-biting in growing-finishing pigs with intact tails: evaluating group size and litter origin
… was to investigate social and behavioral risk factors of tail-biting in pigs with intact tails, using group-level and individual-level approaches, and to evaluate associated welfare outcomes across diverse contexts. Two major research projects were conducted, which are presented across four …
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Viral Delivery of the Fat-1 Gene to Treat Post-Traumatic Arthritis with Diet-Induced Obesity
… cytokines, such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-α,) are more elevated than in non-obese individuals. The role of fatty acids, obesity, and PTA has been examined, with omega-3 fatty acids showing promise as an anti-inflammatory after injury due to its ability to …
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A influência da perda de peso no perfil inflamatório de mulheres com síndrome dos ovários policísticos
… it is common in PCOS the presence of risk factors for developing cardiovascular disease (CVD) and diabetes mellitus, insulin resistance (IR), visceral obesity, chronic low-grade inflammation and dyslipidemia. Due to the high frequency of obesity associated with PCOS, weight loss is …
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Time-restricted eating on inflammation and oxidative stress in overweight, older adults
… of TRE on pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), IL-6, IL-8, and IL-10, as well as oxidative stress related to Alzheimer's disease in humans. Chapter 2 reviews the importance of different types of intermittent fasting (IF) regimens, …
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Mechanisms of soy isoflavones in the regulation of vascular function
… to examine whether genistein protects against tumor necrosis factor-alpha (TNF-α)-induced apoptosis in human aortic endothelial cells (HAECs). The results demonstrated that genistein, at physiologically achievable concentrations (1-10 μM) in individuals consuming soy products, enhanced the …
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Host-microbe interactions in the inflamed gut
… muciniphila produce a soluble and heat-sensitive factor during their concomitant presence that influences cell viability in an in vitro system. We currently hypothesize that this factor is a protein, which has not yet been identified. Based on the potential effect of A. muciniphila on inflammation …
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Novel approaches towards vaccine developments against porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus
… interleukins, such as type I interferons, tumor necrosis factor alpha (TNF-α), interleukin-1 (IL-1), interleukin-6 (IL-6), and interleukin-12 (IL-12) in infected pigs. Antigen-presenting cells (APCs) are the first line of defense, and their infection plays an important role in …
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