Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 93 for “"tumor necrosis factor alpha"”.
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Identifying Depression Utilizing Tumor Necrosis Factor–[alpha] and Endothelial Function in Spinal Cord Injury
… symptomology, biomarker derangement of tumor necrosis factor-alpha (TNF-α), and endothelial function in people with SCI. SCI participants showed higher levels of depression, TNF-α and shorter time to reach maximum level of nitric oxide (NO)-dependent vasodilation. Although these …
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Tumor necrosis factor-alpha- and interleukin-1-induced cellular responses: coupling proteomic and genomic information
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Effects of tumor necrosis factor alpha on nitric oxide synthase in nerve growth factor-responding cells
… accompanied by a decrease in nerve growth factor (NGF)-responsive cholinergic neurons. I report a synergistic effect of the cytokine tumor necrosis factor alpha (TNFa) and NGF on expression of nitric oxide synthase (NOS), in rat pheochromocytoma PC12 cells. NGF/TNFa-promoted iNOS can be …
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Modulation of macrophage tumor necrosis factor-alpha production by omega-3 polyunsaturated fatty acids, eicosanoids, and calcium
Made available in DSpace on 2011-05-07T13:06:27Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9411584.pdf: 5136937 bytes, checksum: e2d5ecc84f036f49d27c51932622b5b8 (MD5) Previous issue date: 1993
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Cellular and Molecular Mechanisms Involved in the Induction of the Lipostatic Cytokine Leptin by Tumor Necrosis Factor Alpha
… that has been identified as a blood-borne factor inherently linking feeding behavior and metabolism to the individual's nutritional state. The studies detailed herein examine hyperleptinemia elicited by tumor necrosis factor (TNF) alpha at many levels. Initial studies determined that …
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Regulation of tumor necrosis factor-alpha induced apoptosis via posttranslational modifications in a human colon adenocarcinoma cell line
… time points during early apoptosis induced by tumor necrosis factor-α
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Regulation of Tumor Necrosis Factor-alpha Signaling in Rheumatoid Arthritis Synovial Fibroblasts by Green Tea Polyphenol Epigallocatechin-3-gallate
… when cytokines, such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α, stimulate synovial fibroblast proliferation leading to joint damage and destruction. Epigallocatechin-3-gallate (EGCG) is a polyphenol found in green tea that has been shown to have an anti-inflammatory effect in RA. …
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Measuring the Changes in Tumor Necrosis Factor-Alpha (TNF-α) from Secretory Populations of U937 Monocytic Cells during Differentiation.
<p>Tumor necrosis factor-alpha (TNF-α) is a cytokine produced primarily by macrophages during acute inflammation. In this study we examined the differential effect of retinoic acid (RA) and phorbol 12-myristate 13-acetate (PMA) on the induction of TNF-α secretion from U937 monocytic cell …
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The production and gene polymorphisms of tumor necrosis factor-alpha in patients with tuberculosis in the Vhembe District, Limpopo Province
… exposed to M.tb, the pro-inflammatory cytokine Tumor Necrosis Factor- α is crucial in host defence against TB and granuloma formation. Therefore, this study aimed to assess the production and gene polymorphisms of TNF-α in patients with TB in the Vhembe district, Limpopo province. Methods: This …
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The mechanism(s) of post-transcriptional regulation of the human constitutive endothelial nitric oxide synthase gene by tumor necrosis factor-alpha
… and molecular oxygen, with the help of cofactors and a heme iron. It is one of three isoforms discovered as yet, and was first identified in endothelial cells lining the blood vessels. Its product, NO, plays a crucial role in the maintenance of vascular tone and homeostasis. Being a gas, …
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The IRAK-1 binding protein SIMPL functions as a p65/RELA co-activator in NF-KB dependent gene expression following tumor necrosis factor-alpha stimulation
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological preconditioning
… infarction can be mimicked by the cytokine tumor necrosis factor alpha (TNFα) but the signalling pathways involved still remain unclear.
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Cytokines in neuroimmunomodulation and neuropathology: Dual expression of the p80 type I and p68 type II interleukin-1 receptors on murine growth hormone producing cells. Murine neurovirulent retrovirus ts-1-MoMulV induces tumor necrosis factor-alpha and nitric oxide secretion from glial cultures in vitro
Restriction data tranferred 2014-07-01T11:18:20-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission
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Childhood Maltreatment is Associated with Adult Depression: Is Inflammation to Blame?
… the world; as such, it is critical to understand factors that contribute to the development of depression. The social signal transduction theory of depression hypothesizes that adversity and social threat upregulate pro-inflammatory biomarkers leading to depression. The current study examined …
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The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis
Tumor necrosis factor alpha (TNFα) is critical for host protective immunity against Mycobacterium tuberculosis infection. TNFRp55 and TNFRp75 can both bind TNFα and conduct signaling, however the respective roles, in particular that of TNFRp75 in an M. tuberculosis aerosol inhalation infection was …
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Evaluation of pediatric acute ulcerative colitis management protocol
… steroids upon discharge were decreased. Anti-tumor necrosis factor alpha was given to more patients earlier upon admission, and the colectomy rate did not change but was more likely to be conducted sooner as an inpatient procedure. While further research with a larger patient population is …
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Association Between Fluoride Exposure and Immune System Biomarkers in Pregnancy
… biomarkers included interleukin (IL)-6, IL-8, tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1 (MCP-1), and C- reactive protein (CRP) from plasma samples collected during the third trimester of pregnancy. Results: We observed a departure from linearity in the association …
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Mapping Major Genetic Factors of Obesity
… of obesity is a result of many different factors, all of which have a base in genetics and can be inherited through generations. Among these factors are eight cell-signaling molecules (adiponectin, leptin, resistin, tumor necrosis factor alpha, plasminogen activator inhibitor one, …
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