Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"tumor motion"”.
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Investigation of Respiratory Motion Management Techniques For Proton and Photon Radiotherapy of Lung Cancer
… as high-energy photons. However, respiratory motion can significantly impact the delivered proton and photon dose distributions during lung cancer radiotherapy. The goals of this dissertation research were to evaluate the impact of respiratory motion and to estimate the benefit of respiratory …
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Towards Intelligent Tumor Tracking and Setup Verification in Radiation Therapy For Lung Cancer
… radiation with high energy to destroy lung tumor cells by damaging their genetic material, preventing those cells from reproducing. The most challenging aspect of modern radiation therapy for lung cancer is the motion of lung tumors caused by patient breathing during treatment. Most gating …
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Improvements In Four-Dimensional and Dual Energy Computed to mography
… the visualization and quantification of object motion. While much research has been done with these technologies, areas remain for potential improvement, both in preclinical and clinical settings, which will be explored in this dissertation. Preclinical dual energy cone-beam CT (CBCT) can …
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Improvements In Robustness and Optimality of Intensity-Modulated Proton Therapy Plans For Lung Cancer Patients With 4-Dimensional Robust Optimization
… of uncertainties associated with breathing motion in treatment planning. The primary objective of this research was to develop a novel four-dimensional robust optimization (4DRO) method and find an appropriate optimization strategy to make IMPT dose distributions less sensitive to both …
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Design and Optimization of Four-Dimensional Cone-Beam Computed to mography In Image-Guided Radiation Therapy
<p>The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning uses models of tumor respiratory motion to account for target motion in targeting. The tumor motion model can be verified …
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Analysis of 3D and 4D proton treatment planning for hepatic tumors
… scans are collected for 25 patients with hepatic tumors treated by proton radiotherapy. The 4D treatment planning process explicitly takes into account respiratory motion of abdominal organs. A 4DCT scan consists of 10 3D anatomical states, each at an instant of time in the respiratory cycle. 4D …
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Motion Estimation and Motion-Compensated Reconstruction for Four-Dimensional Cone Beam Computed Tomography (4D-CBCT)
… few fraction number requires higher accuracy for tumor localization. For organs influenced by the respiration, respiration induced motion becomes the principal cause for tumor localization uncertainty and four dimensional (4D) cone beam computed tomography (CBCT) has been developed to locate tumor …
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Thoracic Radiotherapy Treatment Planning With Cine Pet/Ct
Purpose: Respiratory motion causes substantial uncertainty in radiotherapy treatment planning. Four-dimensional computed tomography (4D-CT) is a useful tool to image tumor motion during normal respiration. Treatment margins can be reduced by targeting the motion path of the tumor. The expense and …
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Development of Five-dimensional Magnetic Resonance Imaging (5D-MRI) for Radiation Therapy
<p>Accurate delineation of tumor target and organs at risk (OARs) is critically important in modern radiation therapy for optimal treatment planning and precise treatment delivery. Conventionally, radiotherapy treatment planning uses 2D X-ray or 3D CT images to assist the delineation of tumor …
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Four-Dimensional Imaging of Respiratory Motion in the Radiotherapy Treatment Room Using a Gantry Mounted Flat Panel Imaging Device
<p>Imaging respiratory induced tumor motion in the radiation therapy treatment room could eliminate the necessity for large motion encompassing margins that result in excessive irradiation of healthy tissues. Currently available image guidance technologies are ill-suited for this task. …
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Prediction of Breathing Patterns Using Neural Networks
… to synchronize the radiation beam with the tumor position. Many compensation techniques have been used before. But all these techniques have some system latency, up to a few hundred milliseconds. Hence it is necessary to predict tumor position to compensate for the control system latency. In …