Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"tumor micro-environment"”.
-
Il-1Α Blockade Reduces Immune Suppression In The Early Tumor Micro-Environment
… Blockade Reduces Immune Suppression in the Early Tumor Micro-Environment</p> <p>Brenda Melendez, B.S.</p> <p>Advisory Professor: Gregory Lizee, PhD.</p> <p>Immunotherapy against melanoma has shown great promise in the clinic for treating advanced-stage patients. However, a major barrier against …
-
Rare-Earth Nanoparticles for Non-invasive In Vivo Imaging of Immune Cells in Cancer Immunotherapy
… Studies have shown that the infiltration of tumors by immune cell subtypes is one of the most significant prognostic indicators of disease-free survival across a large number of cancers. However, we remain limited in our ability to non-invasively sample the continuously evolving tumor …
-
Plasma Extracellular Vessicles, Exercise Resistnace and Cancer
… that iron utilization and homeostasis in the tumor micro environment may play a role in disease progression. Additionally, CD40 was upregulated in individuals with standard cytogenetik risk MM relative to MGUS but was not identified in individuals with high risk MM suggesting that adaptive …
-
Signaling at the Tumor-Immune Interface in Glioblastoma
… of care has not changed in over 20 years. GBM tumors are composed of a milieu of cancer cells and innate immune cells, which are co-opted by the cancer cells to promote an anti-inflammatory environment. Despite tremendous success in immunotherapy in several cancers over the past 10 years, …
-
Development of Novel Therapeutic Strategies for Pancreatic Cancer Treatment
… lab previously established the role of MUC13 in tumor progression and metastasis by alteration of signaling pathways. Recent observations suggest the role of MUC13 in drug resistance and apoptosis in several cancer types. Therefore, it is of great interest to explore the role of MUC13 in …