Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"tumor marker"”.
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Tissue sampling array for tumor marker profiling
… of excised frozen tissue from prostate cancer tumors in patients for conformal mapping of the sampling points to the local tissue geometry. This instrument was designed specifically for use on frozen samples that have been archived and the work involves solving issues inherent in extracting …
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Telomerase : a tumor marker in the peripheral blood of colorectal cancer patients
… to estimate prognosis and may serve as an early marker to assess anti-tumour activity of a treatment. Telomerase is an RNA-dependant DNA polymerase that synthesises telomeric DNA sequences on the tip of chromosomes and is widely considered to be one of the most abundant and common tumour markers. …
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PERSPECTIVES ON THE CLINICAL APPLICATION OF LEWIS ANTIGENS IN PANCREATIC CANCER: TOWARDS A PERSONALIZED TUMOR MARKER STRATEGY
… Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker in gastrointestinal cancers, assuming that it is produced by cancer cells. Recent data has suggested that, in pancreatic ductal adenocarcinoma (PDAC), elevation of CA19.9 could depend on its reabsorption in the bloodstream. No specific …
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Tumoros betegségek laboratóriumi markereinek vizsgálata és többparaméteres számítógépes analízise
Tumor markerek elemzése kemilumineszcens immunoassay módszerrel. A heretumoros betegeknél mind az AFP, mind a béta-HCG jó szenzitivitással és specificitással jelezte a tumor jelenlétét. A laboratóriumban végzett tumor marker eredmények analízise azt mutatta, hogy a keringő tumor markereke általam …
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Ισοένζυμα γαλακτικής δεϋδρογενάσης και παθολογία του προστάτη
… prostate glands. The ratio LDH₅/LDH₁ is a “tumor marker” for a early diagnosis of the cancer of the prostate.
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Understanding tumor cell plasticity in spatial transcriptomics with graph attention networks and walk-based pseudotime analysis
Tumor cell plasticity in cancer is a key driver in tumor progression, heterogeneity, metastasis, and treatment resistance. Tumor cells change states from the conventionally easier to treat epithelial state to the more resistant mesenchymal state. Understanding the transition dynamics of these …
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Untersuchung der relativen Serum-Trisialotransferrin-Konzentration als möglicher prädiktiver Biomarker für hepatozelluläre Dedifferenzierung bei chronisch fibrogener Lebererkrankung
… (HCC). Up to now the spectrum of valid serum biomarkers for this process of hepatocellular dedifferentiation is very limited. Thus, we investigated the dynamics of alterations in the serum transferrin isoform pattern in the pathogenetic sequence from liver fibrosis to hepatocellular carcinoma, in …
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Microelectromechanical handheld laser-scanning confocal microscope: application to breast cancer imaging
… and expression levels of specific molecular markers. Since 85% of cancers are known to originate in the epithelium, portable in vivo imaging techniques providing sub-cellular detail in tissue up to depths of 250 μm could help improve access to biopsy-free examination in low-infrastructure …
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ESPRESSIONE DI SEL1L NEL CARCINOMA MAMMARIO - CORRELAZIONI CLINICO PATOLOGICHE
… various aspects of malignant transformation and tumorigenic processes, providing significant in vitro and in vivo evidences to link its increased expression to a decrease in breast tumor aggressiveness. In this study it has been suggested that SEL1L protein could be also a tumor breast markers …
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Testicular cancer – response adapted treatment, prognostic markers and survivorship issues
… intensified treatment to these individuals. Tumor marker decline and, for patients with marker negative disease, radiological assessment were to be used for response evaluation. The conclusion was that with detailed treatment protocols and a dedicated collaborative group of specialists, …
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Development and characterization of anti-EGFR protein-drug conjugates for tumor therapy
… combine the ability of an antibody to target tumor-specific antigens with the cell-killing potential of a cytotoxic payload after cellular internalization. The epidermal growth factor receptor (EGFR) is a validated tumor marker overexpressed in various cancers such as squamous cell carcinoma …
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Vergleichende Etablierung und Charakterisierung eines orthotopen Kolonkarzinom-Xenograft-Modells
… into the cecal wall and orthotopic fixation of a tumor fragment onto the cecum. The subcutaneous experiment took 41 days; the orthotopic animal experiments were equally divided into three points of necropsy each two weeks apart. On these days tumor, liver and lung were withdrawn, fixed in 3,8% …
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Ανάπτυξη και κλινικές εφαρμογές μεθόδων μοριακής διαγνωστικής για την ανίχνευση κυκλοφορούντων καρκινικών κυττάρων στον καρκίνο του μαστού μέσω της έκφρασης της μαστοσφαιρίνης α
… and has been recently evaluated as a molecular tumor marker for the detection of circulating breast cancer cells. The aim of our study was to develop a sensitive and specific method for the detection of Mammaglobin A -mRNA positive cells in peripheral blood of breast cancer patients. The method …
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Charakterisierung des humanen Proteins MCM8 und seiner Interaktion mit CDC45
… weitgehend unbekannt. Durch Untersuchungen von Tumorgeweben wurde gezeigt, dass humanes MCM8 in den entsprechenden Zellen akkumuliert oder mutiert vorliegt. Dies lässt darauf schließen, dass MCM8 an der Entwicklung von Tumoren beteiligt sein könnte. Für das Verständnis der Krebsentstehung ist …
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A new prompt gamma spectroscopy-based approach for range verification in proton therapy
… translates into a high dose conformality in the tumor, as well as into a superior sparing of normal tissue compared to conventional radiotherapy with photons. Today, there are 107 proton therapy and 14 carbon ion centers operating worldwide, and many new ones are under construction. In Italy, the …