Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 573 for “"tumor growth"”.
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Nonlinear simulation of tumor growth and chemotherapy
… for free boundary necrotic and non-necrotic tumor growth and chemotherapy, where the tumor-healthy tissue interface is a moving deformable boundary. In the process, we improve upon existing techniques and develop new finite difference and ghost fluid / level set methods to attain full …
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Analysis and numerical simulation of tumor growth models
… we focus on the numerical analysis of tumor growth models. Due to the difficulty of developing physically meaningful approximations of such models, we divide the main problem into more simple pieces of work that are addressed in the different chapters. First, in Chapter 2 we present a …
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Mathematical Models of Prevascular Tumor Growth by Diffusion
… describe the early, prevascular stages of solid tumor growth by diffusion under various simplifying assumptions is presented. The advantage of these models is that their degree of complexity is relatively low, which ensures fairly straightforward comparisons with experimental or clinical data (as …
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Analysis and numerical simulation of tumor growth models
… we focus on the numerical analysis of tumor growth models. Due to the difficulty of developing physically meaningful approximations of such models, we divide the main problem into more simple pieces of work that are addressed in the different chapters. First, in Chapter 2 we present a …
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Mathematical Modeling of Vascular Tumor Growth and Development
… ranging from the more broad systems, avascular tumor models, to smaller systems, models of angiogenic pathways. A preliminary model of a vascularized tumor has been developed; the model is based on fundamental principles of mechanics and will serve as the framework for a more detailed model in …
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Discrete Fractional Calculus and Its Applications to Tumor Growth
… theory. Some applications of the theory to tumor growth are also studied. <br> The first chapter is a brief introduction to discrete fractional calculus that presents some important mathematical functions widely used in the theory. The second chapter shows the main fractional difference and …
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The Effect of Tim-3-Ig on Tumor Growth
… but it's function has not been clarified in tumor immunity. To explore the effect of Tim pathway blockade on tumor growth using Tim-3-Ig fusion protein, two approaches were adopted. First, it was investigated whether Tim-3-Ig expression in lung carcinoma cells (3LL) affects tumor growth in …
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Medical image registration on tumor growth with time series
DSpace SAF Submission Ingestion Package generated from Vireo submission #10029 on 2016-11-09 at 10:25:43
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Discrete model for cancer tumor growth and effect of chemotherapy
<p>Many mathematical models have focused on growth of a single tumor with their spreading rate with some have included its metastasis. Some of the earlier models focus on exponential growth and its shift with time on to a linear model. The Gompertzian model involves a quadratic terms and that limit …
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Changes in macrophage functions and gene expression during tumor growth
… and phenotypes change in macrophages (Mφ) during tumor growth. Although analyzing functional and phenotypic changes are important in understanding the mechanism of tumor-induced immunosuppression, it is necessary to look beneath the surface and expose the mechanisms behind these changes. Flow …
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Regulation of macrophage activities by tumor growth: mechanisms of immunosuppression
… (Mφ) are a major immune cell involved in anti-tumor responses. Mφ activities such as tumor cytotoxicity. presentation of tumor-associated antigens, and stimulation of anti-tumor lymphocytes are all involved in the battle against tumor growth. However, other Mφ activities such as cell growth …
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The role of pyruvate kinase regulation in tumor growth and metabolism
… disrupt proliferative metabolism and hinder tumor growth. We found that increased PK activity due to expression of the constitutively-active PKM1 isoform or direct pharmacological activation of PKM2 perturbs metabolism and reduces tumor growth in a lung cancer xenograft model. These results …
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The Role of the Aryl Hydrocarbon Receptor in Tumor Growth and Chemoresistance
… these environmental toxins can contribute to the growth and chemoresistance of OSCCs. Nude mice tongues were injected with a human OSCCs cell line, SCC2s, and treated with an AHR antagonist at 25mg/kg daily via oral gavage. Primary tumor growth was measured via calipers and IVIS imaging. RT-qPCR …
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NABLA Fractional Calculus and Its Application in Analyzing Tumor Growth of Cancer
… the model which fits best for the data of tumor growth for twenty-eight mice. The models contain either three parameters (Gompertz, Logistic) or four parameters (Weibull, Richards). For each model, we consider continuous, discrete, continuous fractional and discrete fractional forms. Nihan …
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Chronic Stress Promotes Tumor Growth Through Increased Bdnf Production and Neo-Innervation
… of adrenergic signaling, which promotes tumor growth and progression. However it is unknown how catecholamine levels within the tumor exceed systemic levels in circulation. I hypothesized that neo-innervation of tumors is required for stress-mediated effects on tumor growth.</p> …
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Altered Ovarian Cancer Metabolism Increases Neuronal N-Acetylaspartate to Promote Tumor Growth
… cancers. Inhibiting NAA production decreases tumor growth, and tilts the cancer cell to a more catabolic steady state. Therefore, our data indicate that targeting cancer’s NAA production maybe an effective therapeutic approach.</p>
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Influence of social housing conditions on mouse mammary tumor growth and behavior
… psychosocial variables that may influence growth of the Shionogi mouse mammary carcinoma (SC115). Change in social housing condition, direction of change [individual to group (IG) or group to individual (GI)), group size, sibling relationship and dominance were the major variables examined. …
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Eukaryotic Initiation Factor 5A2 (EIF5A2) Contributes to Ovarian Tumor Growth and Metastasis
<p>Ovarian cancer has the highest mortality rate among all gynecological malignancies due to lack of effective biomarkers for early diagnosis. The majority of ovarian cancer patients are already at an advanced stage when diagnosed. In addition, ovarian cancers often become chemoresistant and …
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