Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"tumor associated macrophage"”.
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The Biomechanical Role of Cancer-Associated Fibroblasts In Tumor-Stroma Reciprocity
… stimuli have been found to influence tumor cell proliferation and metastasis with increased stiffening of the extracellular matrix being a hallmark of tumorigenesis. This thesis examines the role of the extracellular environment surrounding tumors, the tumor stroma, and investigates …
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ELUCIDATING THE FUNCTIONS OF TAp73 IN BREAST CANCER
… results suggested that TAp73 can function as a tumor promoter in tumorigenic cells and as a tumor suppressor in cancer-associated fibroblast and tumor-associated macrophage. The PyMT mice with TAp73 knockout in the tumorigenic mammary epithelial cells had a longer latency in the development of …
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Role of the Abelson Tyrosine Kinases in Regulating Macrophage Functions in Immunity and Cancer
… for Abl kinases in regulating the efficiency of macrophage phagocytosis and inflammatory responses. Bone marrow-derived macrophages from mice lacking Abl and Arg kinases exhibit inefficient phagocytosis of sheep erythrocytes and zymosan particles. Treatment with the Abl kinase inhibitors imatinib …