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Showing 1 to 7 of 7 for “"tuberculosis associated immune reconstitution inflammatory syndrome"”.

  1. Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors

    Background: In a proportion of patients with HIV-associated tuberculosis who develop paradoxical immune reconstitution inflammatory syndrome (IRIS), the clinical course of IRIS is prolonged necessitating substantial health care utilization for diagnostic and therapeutic interventions. This …

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  2. Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome

    … the integration of anti-TB and cART therapies is associated with substantial clinical improvement in the majority of patients, HIV-Tuberculosis associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS) has been shown to occur in a significant subset of these patients. TB-IRIS is an …

    cape-town Repository record for Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome (opens in a new tab)

  3. Investigating the molecular pathogenesis of tuberculosis-associated immune reconstitution inflammatory syndrome

    … underlying the immunopathogenesis of paradoxical tuberculosis associated immune reconstitution inflammatory syndrome (TB-IRIS). Paradoxical TB-IRIS is an aberrant immune response targeted against Mycobacterium tuberculosis or its residual antigens in patients with advanced human immunodeficiency …

    cape-town Repository record for Investigating the molecular pathogenesis of tuberculosis-associated immune reconstitution inflammatory syndrome (opens in a new tab)

  4. Diagnosis, treatment and immunopathogenesis of the HIV-associated tuberculosis immune reconstitution inflammatory syndrome

    The paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a frequent complication of antiretroviral therapy (ART) among patients who start ART while on treatment for tuberculosis (TB). The condition manifests with new, worsening or recurrent inflammatory

    cape-town Repository record for Diagnosis, treatment and immunopathogenesis of the HIV-associated tuberculosis immune reconstitution inflammatory syndrome (opens in a new tab)

  5. The immunomodulatory role of prednisone in patients with HIV-associated tuberculosis and assessment of its impact on lung function outcome

    … on immunopathology and pulmonary function in HIV-associated tuberculosis and tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS). I do this using data collected during the PredART trial. This randomized, double-blind, placebo-controlled trial showed that a 28-day course …

    cape-town Repository record for The immunomodulatory role of prednisone in patients with HIV-associated tuberculosis and assessment of its impact on lung function outcome (opens in a new tab)

  6. Modulation of protein expression in Mycobacterium tuberculosis-stimulated TB- IRIS patient-derived PBMCs by omega n-3 polyunsaturated fatty acids

    Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory disorder which affects up to 54% of TB-HIV co-infected patients. Its pathogenesis remains unclear, and although treatment with the corticosteroid prednisone has shown some benefits, there is no specific …

    cape-town Repository record for Modulation of protein expression in Mycobacterium tuberculosis-stimulated TB- IRIS patient-derived PBMCs by omega n-3 polyunsaturated fatty acids (opens in a new tab)