Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"tsetse flies"”.
-
The evolution of immune genes in tsetse flies (Glossina) and insights into tsetse-symbiont-trypanosome interactions
Tsetse flies (genera Glossina) are the sole biological vectors of African Trypanosoma species, the infectious agents of African Trypanosomiasis. Vector control is a key inhibitor of disease transmission; however, long-term control measures are economically and ecologically unsustainable and …
-
Molecular characterization of trypanosomes commonly found in cattle, wild animals and tsetse flies in Kwazulu-Natal, South Africa, 2005-2007
… trypanosomes in cattle, wild animals and tsetse flies in KwaZulu-Natal, thus contributing to improved understanding of the genetic diversity of trypanosome species infecting cattle at the game/livestock interface in the KwaZulu-Natal Province of South Africa. Primers based on sequences of …
-
Epidemiological role of indigenous dogs in the transmission of animal and human African trypanosomiasis in Zambia: a case study of dogs from Mambwe District
… African trypanosomiasis (AT) is endemic in tsetse-infested Mambwe district. Although cases are common in livestock, they are rarely reported in dogs. However, recent studies have detected trypanosomes in Zambian dogs. As a follow-up, the current research was designed to investigate what …
-
Prevalence of human African trypanosomiasis and its associated risk factors in Itezhi-tezhi district of Zambia.
… caused by trypanosomes which are transmitted by tsetse flies of the genus Glossina. This study aimed to determine the prevalence and risk factors of HAT in Itezhi-Tezhi (ITT) District of Zambia through active surveillance. Human infective trypanosomes have been demonstrated to be in circulation …
-
An evolutionary genomics approach towards analysis of genes implicated in transmission of trypanosomes between tsetse fly and mammalian host
… any of the three players,the human host, the tsetse fly vector and/or the parasite. The human genome has been deciphered and the genomes of several trypanosome species have been sequenced. Sequencing of additional neglected trypanosome species is in progress. The tsetse fly genome is currently …
-
Characterising the bacterial microbiota of Phlebotomus and Glossina insects : vectors of parasitic diseases
… and transmitted between human hosts by biting flies. In this thesis the bacterial microbiota of tsetse flies and sand flies, the vectors of trypanosomiasis and leishmaniasis respectively, were examined using molecular biology and next generation sequencing to understand their distribution in …
-
Some aspects of the behaviour,ecology and vectorial capacity of glossina brevipalpis newstead and other flies in the Luangwa valley of Zambia
… the year. It was, however, observed that the flies were attracted to the traps but did not enter. Glossina brevipalpis was not easy to catch with ordinary fly rounds, but with the use of an electric screen fly round, more of this fly were caught. The best sampling system for G. brevipalpis was …
-
Some aspects of the behaviour,ecology and vectorial capacity of glossina brevipalpis newstead and other flies in the Luangwa valley of Zambia
… the year. It was, however, observed that the flies were attracted to the traps but did not enter. Glossina brevipalpis was not easy to catch with ordinary fly rounds, but with the use of an electric screen fly round, more of this fly were caught. The best sampling system for G. brevipalpis was …
-
Structure- based inhibitor design for key enzymes of <em>Tryposoma brucei</em>
… brucei</em>. These parasites are transmitted by tsetse flies and endanger over 60 million people in Sub-Saharan Africa. Untreated, sleeping sickness is fatal, causing at least 48.000 deaths per year. Its treatment remains complicated since the currently available drugs show high toxicity and are …
-
A comparative genomics approach towards classifying immunity-related proteins in the tsetse fly
Tsetse flies (Glossina spp) are vectors of African trypanosome (Trypanosoma spp) parasites, causative agents of Human African trypanosomiasis (sleeping sickness) and Nagana in livestock. Research suggests that tsetse fly immunity factors are key determinants in the success and failure of infection …
-
Establishing Sodalis species as a laboratory model of endosymbionts
… spp., the viviparous, obligate blood feeding (tsetse) flies that populate sub Saharan Africa, are of interest within symbiont research as they play host to at least four bacterial symbionts, with diverse phenotypes: Wigglesworthia, Wolbachia, Spiroplasma and Sodalis. Sodalis glossinidius – a …
-
Synthetic strategies for potential trypanocides
… which are transmitted by the bite of infected tsetse flies. Although the disease is fatal if left untreated, there is a lack of safe, effective and affordable drugs available; therefore new drugs are urgently needed. The aim of the work presented in this thesis is to develop novel trypanocidal …
-
Effects of Trypanosoma brucei brucei on spatial learning and memory
… by trypanosome parasites and transmitted through tsetse flies. The HAT is clinically defined by two diagnostic stages, commencing with an early-stage also known as the haemolymphatic stage where parasites appear to be localised in the blood and lymphatic systems, then a late-stage/ …
-
Prevalence and risk factors associated with Trypanosomosis in Cattle Herds in Kilwa District of Lindi Region of Tanzania
… factors associated with bovine trypanosomosis in tsetse-infested Kilwa district, Lindi region, Southern Tanzania. Blood samples were collected from 420 cattle randomly selected from 86 herds from ten villages. A maximum of ten herds per village and at maximum six animals from each herd were …
-
Prevalence and risk factors associated with Trypanosomosis in Cattle Herds in Kilwa District of Lindi Region of Tanzania
… factors associated with bovine trypanosomosis in tsetse-infested Kilwa district, Lindi region, Southern Tanzania. Blood samples were collected from 420 cattle randomly selected from 86 herds from ten villages. A maximum of ten herds per village and at maximum six animals from each herd were …