Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"trypsinogen"”.
-
Signaling and Adhesive Mechanisms in Acute Pancreatitis
… It is widely held that premature intra-cellular trypsinogen activation and leukocyte recruitment play key roles in the pathophysiology of the AP. However, the signaling and adhesive mechanisms remain elusive. The aim of this thesis was to investigate the signaling and adhesive mechanisms in AP. …
-
Analysis of the antifreeze glycoprotein containing genomic locus in the Antarctic notothenioid fish dissostichus mawsoni
… avoidance strategy. The AFGP gene evolved from a trypsinogen-like protease (TLP) gene, and presumably through an ancestral intermediate, a chimeric AFGP/TLP gene. All three types of genes (TLP, AFGP, and chimeric AFGP/TLP) are found in Antarctic notothenioid genomes, but it is not known whether …
-
Antifreeze Glycoproteins of Two Unrelated Polar Fishes: Gene Structure, Organization and Evolution
… cod AFGP genes show no sequence identity with trypsinogen gene, indicating trypsinogen gene is not the progenitor of this group of AFGP genes. The southern and northern AFGP genes also have different signal peptides, different intron-exon organizations, different spacer sequences thus are the …
-
Metabolic and Lifestyle related risk factors for pancreatic cancer
… between alcohol and pancreatic cancer, between trypsinogen, pancreatic secretory trypsin inhibitor (PSTI) and pancreatic cancer, between Helicobacter pylori infection and pancreatic cancer and to investigate if the metabolic syndrome is associated with the risk of pancreatic cancer. Results and …
-
Acute Pancreatitis. Studies on smoking and protease activation.
… Results and conclusions: Cathepsin B activated trypsinogen but not proelastase or procarboxypeptidase B. Hence, if cathepsin B is to play a role in the activation of digestive enzymes in acute pancreatitis, this probably occurs through activation of trypsinogen. The incidence of …
-
Preparation of 7-(p-Substituted-Benzylamino)-4-Nitrobenzoxadiazole Derivatives and the Study of their Fluorescent Properties in Solution
… to determine the conformation changes of bovine trypsinogen and bacterial libosomes. Fluorescent probes have been used to: (l) establish the degree of polarity of a particular region of a protein; (2) measure distances between groups in a protein; (3) determine the extent of a flexibility of a …
-
Comparison of the Protein Contents of Bovine Zymogen Granules and of Pancreatic Juice
… employed by Keller, Cohen and Neurath. Trypsinogen, chymotrypsinogen A, ribonuclease, amylase, chymotrypsinogen B, procarboxypeptidase B, deoxyribonuclease and procarboxypeptidase A have been located in the chromatograms as 13 distinct peaks on the effluent curves. Complete recovery of …
-
Characteristics and Performance of Novel Squarylium Dyes as Fluorescent Probes for the Analysis of Proteins and Viruses by CE-LIF
… serium albumin (HSA), myoglobin, transferrin, trypsinogen, and bovine serium albumin (BSA) and was also used in the separation of a complex mixture of these proteins. Also examined were dyes SQHN-3c, SQHN-102, SQHN-103, and SQHN-105, which contain a single squaric acid center with various …
-
A study of a multi-systemic immune-mediated disease in the English Cocker Spaniel
… receptor beta variable loci and the anionic trypsinogen gene, was rejected. The SNP rs852916308 was not polymorphic in ECS. Results found on the SNP rs22196038 located on chromosome 12, which is downstream of the branched-chain alpha-keto acid dehydrogenase BCKDHB gene, demonstrated some …
-
Fibrinolysis by bile
… and arginine (BAEE). It is inactive against trypsinogen, chymotrypsinogen and plasminogen. Isolation and purification of this protease from ox bile proved complex, and was finally achieved by an 8 step procedure which yielded a dry white powder, stable for 45 months (to date) at 4°C. Quality …
-
Isoprenylation and NET formation in acute pancreatitis
Acute Pancreatitis (AP) is an inflammation disease that characterized by activation of protease and the innate immune system, leading to infiltration of neutrophils and tissue damage in the pancreas. The aim of this thesis was to determine the role of isoprenylation (farnesyltransferase and …
-
Molecular mechanism of magnesium transport in epithelial cells
… can result in marked increases in amylase and trypsinogen output in normal (1.1 mlvi) extracellular magnesium [Mg 2 0. When [Mg2 0 was elevated to 10 mlvi, there was a significant (P C 0.05) decrease in secretagogue-evoked pancreatic enzyme secretion. On the other hand, in low (0 mM) [Mg2 0 …