Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"trypsin-like proteases"”.
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An investigation of the cellular effects of novel agents and multi-drug combinations in cystic fibrosis
… include the inhibition of overactive ENaC. As proteases released from host epithelial and inflammatory cells and bacteria in CF airways, principally trypsin-like proteases (TLPs), play a role in activating ENaC, inhibition of these channel activating proteases (CAPs) represents a novel …
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Molecular biology of the entomopathogenic fungus Beauveria bassiana : insect-cuticle degrading enzymes and development of a new selection marker for fungal transformation
… supporting the role of cuticle-degrading proteases (PR1 and PR2) as well as phospholipase B (PLB) in fungal pathogens and their correlations to virulence observed in either M. anisopliae or C. albicans, these genes were cloned from B. bassiana 252. Two PLB-encoding genes (plb1 and plb2, …
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The development of novel strategies to modulate epithelial sodium channel (ENaC) activity in chronic obstructive pulmonary disease (COPD)
… inhibitory activity against human airway trypsin-like (HAT) protease, matriptase, and prostasin. QUB-2136 was capable of inhibiting amiloride short-circuit current to a greater extent and for a longer period of time when compared to QUB-1916. However, further evaluation of QUB-2136 …