Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 77 for “"trypanosomiasis"”.
-
Population dynamics of African Trypanosomiasis
… observed between epidemics.A model of animal trypanosomiasis is compared against fielddata from the International Trypanotolerance Centre, TheGambia. Tsetse population parameters were investigated in arecapture study, and a method of analysis of these data whichallows for cyclic availability …
-
Some clinical observations on trypanosomiasis rhodesiensis
1. The object of the paper is to record some clinical observations made during the study of 94 consecutive cases of Rhodesian Sleeping Sickness.
-
New therapeutic strategies against trypanosomiasis and leishmaniasis
Leishmaniasis and African Trypanosomiasis are diseases caused by the Kinetoplastida parasites of Leishmania sp. and Trypanosoma sp. respectively. Control and management of these diseases, which affect a significant number of people in the tropics and subtropical areas of the world, is beset with …
-
Macrophage cytokines as correlate of differential resistance to African trypanosomiasis
… macrophages play a central role in resistance to trypanosomiasis. The expression of mRNA and/or production of cytokines (IL-6, IL-10, TNF-α, TGF-β1 and IL-12) and nitric oxide (NO) by macrophages from C57Bl/6 and BALB/c mice in response to 'T. congolense' or 'T. brucei' were studied. The bone …
-
African trypanosomiasis : its effect on platelet morphology, function and survival
Thrombocytopenia, occurring sometimes in conjunction with disseminated intravascular coagulation, has been reported sporadically in both human and animal trypanosomiases. The extent of the thrombocytopenia and its relationship to the anaemia and parasitaemia has been investigated in experimental …
-
Putative phosphodiesterase inhibitors as potential new chemotherapies against African Trypanosomiasis
African trypanosomiasis is a disease caused by the Kinetoplastida parasites Trypanosoma brucei rhodesiense and T. b. gambiense. The distribution of the disease is split geographically with T. b. rhodesiense found in eastern sub-Saharan Africa and T. b. gambiense in the west of the continent. …
-
Discovery and development of diagnostic biomarkers for human African trypanosomiasis
<p>Human African Trypanosomiasis (HAT) or African Sleeping Sickness is a disease prevalent in many parts of Sub-Saharan Africa. HAT is a parasitic infection caused by two species, <em>Trypanosoma brucei gambiense</em> and <em>T. b. rhodesiense</em>. Clinical diagnosis is not sufficient as symptoms …
-
Examination and management of human African Trypanosomiasis propagation using geospatial techniques
Human African Trypanosomiasis (HAT) is a vector-borne disease transmitted by the bite of the tsetse fly that results in high human morbidity and mortality. The propagation of the disease has been linked to environmental factors, and understanding the vector’s habitat is vital to its control. There …
-
The role of erythropoietin in the pathophysiology of anemia associated with trypanosomiasis
African trypanosomiasis is one of the most important hemoprotozoan diseases affecting both humans and livestock in sub-Saharan Africa. A blunted erythropoietin (Epo) response has been proposed as one possible mechanism that contributes to the nonresponsive anemia in trypanosome-infected cattle. The …
-
Factors influencing the spread and selection of drug resistance in Human African Trypanosomiasis
… problem with drug resistance in Human African Trypanosomiasis has necessitated the implementation of screening programmes to monitor for its spread. This thesis describes the study of several factors that can influence the selection and propagation of drug resistance in T. brucei. Human African …
-
Determination of the role of cytokines using gene deficient mice in African trypanosomiasis infection
African trypanosomiasis encompasses diseases caused by pathogenic trypanosomes, infecting both humans and animals alike. To determine the immunological role of IL=12 family members in Trypanosoma brucei brucei, Trypanosoma evansi and Trypanosoma congolense infections, IL-12p35¯/¯, IL-12p40¯/¯ and …
-
Economic and social consequences of human african trypanosomiasis in Muchinga, Lusaka and Eastern provinces of Zambia
Human African Trypanosomiasis (HAT) causes severe economic production losses in humans due to loss of man power and death. In Zambia most of the studies that have been done have focused on analysing the parasite while none have been conducted to establish the economic consequences of the burden of …
-
Prevalence of human African trypanosomiasis and its associated risk factors in Itezhi-tezhi district of Zambia.
Human African Trypanosomiasis (HAT) is a debilitating zoonotic disease caused by trypanosomes which are transmitted by tsetse flies of the genus Glossina. This study aimed to determine the prevalence and risk factors of HAT in Itezhi-Tezhi (ITT) District of Zambia through active surveillance. Human …
-
Economic and social consequences of human african trypanosomiasis in Muchinga, Lusaka and Eastern provinces of Zambia
Human African Trypanosomiasis (HAT) causes severe economic production losses in humans due to loss of man power and death. In Zambia most of the studies that have been done have focused on analysing the parasite while none have been conducted to establish the economic consequences of the burden of …
-
Molecular epidemiology of trypanosomiasis in Ugandan cattle during the Stamping Out Sleeping Sickness control programme, 2006 – 2008
… to reduce the prevalence of Human African Trypanosomiasis (HAT) in the newly affected districts by reducing the prevalence of this parasite in the main animal reservoir of infection – domestic cattle. Cattle were mass treated using trypanocides to clear infections. Previous work …
-
Epidemiological role of indigenous dogs in the transmission of animal and human African trypanosomiasis in Zambia: a case study of dogs from Mambwe District
In Zambia, African trypanosomiasis (AT) is endemic in tsetse-infested Mambwe district. Although cases are common in livestock, they are rarely reported in dogs. However, recent studies have detected trypanosomes in Zambian dogs. As a follow-up, the current research was designed to investigate what …
-
Published papers
… in the Ilorin Province of Northern Nigeria. • 3. Trypanosomiasis of Domestic Animals in Northern Nigeria. • 4. On the Morphology of the Trypanosome (T. nigeriense, n. sp . ) from a Case of Sleeping Sickness from Eket, Southern Nigeria. • 5. On the Pathogenicity of the Trypanosome (T. nigeriense) …
-
A comparative study on the capacity of Health Workers and Health Centers to diagnise Human African Trypanosomiasis in Tsetse infected Chama and Mambwe Districts of Eastern Zambia
… compare the levels of knowledge on Human African Trypanosomiasis (HAT), disease awareness among health personnel and factors affecting the diagnostic capacity of HAT in tsetse infested Chama and Mambwe districts of Eastern Zambia. Structured questionnaires were used to collect information from 110 …
Page 1 of 4