Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"tropisms"”.
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A Re-Examination of Animal Tropisms
Made available in DSpace on 2014-12-10T21:07:31Z (GMT). No. of bitstreams: 1 7310024.pdf: 2855833 bytes, checksum: d63d0a6d4dc7e1c0cee1af109e726347 (MD5) Previous issue date: 1972
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A hybrid mathematical model of fungal mycelia: tropisms, polarised growth and application to colony competition
… orientation scheme that facilitates a variety of tropisms to different influential factors. The hybrid model is used to investigate several scenarios such as the polarisation of growth in response to isolated nutrient resources, competition between multiple colonies and fungal development and …
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PIECING TOGETHER THE PUZZLE OF TREATING HEMOPHILIA A UTILIZING AAV BASED GENE THERAPY
… technology more recently developed, new viral tropisms can be identified. In the experiments conducted we utilized cloning to generate plasmids containing only one ITR. Our work shows that plasmids containing only a single ITR can be packaged into virions during normal rAAV production. This is …
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Characterization of Arabidopsis thaliana mutants defetive in auxin metabolism
… elongation, cell division, apical dominance, tropisms, and fruit ripening. The most abundant naturally occurring auxin is indole-3-acetic acid (IAA). IAA is found in plants both as the free acid and in conjugated forms. It is believed that the balance between IAA biosynthesis, metabolism, and …
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Genome scale identification of HIV Dependency factors across multiple HIV-1 strains
… different clades and with different co-receptor tropisms. Nearly all of the host dependency factors were validated in subsequent follow-up studies and there was a direct relationship between the scoring of a dependency factor in the screen and its effect on HIV replication in validation studies. …
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West Nile virus versus the host cell: Identification of host factors that modulate infection
… may control the level of viral replication, host tropisms and, ultimately, viral pathogenesis. To identify host co-factors that are essential for WNV infection and/or replication, small interfering RNAs (siRNAs) were used to systematically knockdown host gene products and levels of WNV infection …
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Reciprocal communication between cancer cell and tumor microenvironment promotes breast cancer metastasis
… metastatic cells lines with distinct organ tropisms and found miR-19a is specifically up-regulated in the serum exosome of patients with bone metastases, as well as exosome from bone metastatic cell lines. MiR-19a in the exosome is able to induce osteoclast activity in vitro. Knockout of …
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Structural determinants of murine leukemia virus (MLV) reverse transcriptase (RT) important for fidelity and drug resistance in vivo
… generating mutants that exhibit altered host tropisms, resistance to antiviral drugs, and the ability to escape the host's immune system. To identify structural elements of murine leukemia virus (MLV) RT important for fidelity and drug-resistance in vivo, we developed a D17-based encapsidating …
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Characterization of the molecular and biological determinants of viral dissemination from the mosquito midgut: Yellow feber virus in Aedes aegypti
… 4B (NS4B). \r\nThe virus distribution and tissue tropisms Asibi, 17D, and a chimera 17D/Asibi M-E were evaluated in whole-sectioned Ae. aegypti by immunohistochemistry to characterize the temporal and spatial aspects of YFV dissemination. Data from these studies suggest the following sequence of …
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Development of novel chemical biology tools to probe malaria parasite physiology and aid in antimalarial drug discovery
… mechanisms underlying parasite invasion tropisms. Future receptor designs could promote the invasion of P. vivax into mature red blood cells and potentially facilitate practical in vitro culture. Taken together, these tools present new opportunities for drug discovery to aid efforts in …
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Survival strategies of Mycobacterium avium subsp. paratuberculosis in a variety of microenvironments.
… bacilli that encompass a wide-range of host tropisms and diseases. Mycobacteria can be divided into two complexes: the Mycobacterium tuberculosis complex and the Mycobacterium avium complex (MAC). The MAC is comprised of M. avium subsp. avium (M. avium), MAP, M. intracellulare and M. avium …
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PATTERNS OF NATURAL SELECTION ASSOCIATED WITH TROPISM SHIFTS IN ANIMAL CORONAVIRUS GENOMES
… from sequences isolated from two separate feline tropisms (gastrointestinal and macrophage) to identity which adaptive mutations may be associated with the tropism shift and subsequent shift in virulence. This was performed on Feline Coronavirus (FCoVs), where almost 90% of all wild and domestic …
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Transport phenomena in plant-internal processes: growth and carbon dioxide transport
… and torsion, as becomes clear particularly in tropisms (e.g. gravitropism, hydrotropisms and phototropism). Although these processes are known for a long time in biology, no suitable measures to characterize the production of curvature and torsion have been defined. Using a curvature and …
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Wolbachia colonization in drosophila midguts and its effects on intestinal stem cells
… will aid in our understanding of Wolbachia tropisms and its phenotypic consequences. It has been shown that in the Wolbachia wMelPop strain excessive growth of intracellular bacteria leads to damage to the host cell, suggesting a mechanism of controlling intracellular growth in other …
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Die Rolle von Kaliumkanälen der AKT1-Unterfamilie für Kaliumaufnahme und gerichtetes Wachstum
In vorausgegangenen Experimenten unseres Labors war bereits gezeigt worden, dass die Transkription des Kaliumaufnahmekanals ZMK1 durch IAA stimuliert wird und dass dieser eine wichtige Rolle für das differentielle Zellstreckungswachstum während der gravitropen Krümmung spielt. Dieser Annahme …